Epidemiology, molecular, and genetic methodologies to evaluate causes of CKDu around the world: report of the Working Group from the ISN International Consortium of Collaborators on CKDu
Twenty years ago, nephrologists working in El Salvador and Sri Lanka described a progressive kidney disease leading to devastatingly high rates of death from kidney failure in young and middle-aged individuals.1,2 Other descriptions including documentaries and press reports brought chronic kidney disease of unknown etiology (CKDu) to the world ’s attention, presenting the toll on working families unable to afford kidney replacement therapy.3 Additional regions with a similar profile of kidney disease have since been discovered, but few rigorous studies have been performed to investigate candidate hypotheses.
Source: Kidney International - Category: Urology & Nephrology Authors: Shuchi Anand, Ben Caplin, Marvin Gonzalez-Quiroz, Stephen L. Schensul, Vivek Bhalla, Xavier Parada, Nishantha Nanayakkara, Andrew Fire, Adeera Levin, David J. Friedman, International Society of Nephrology ’s International Consortium of Collaborators on Tags: Nephrologists Sans Fronti ères Source Type: research
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