Adiposity is related to neuroelectric indices of motor response preparation in preadolescent children

ConclusionsThe results suggest that while different cognitive functions may be affected by health-related characteristics, stimulus evaluation and motor activation may be particularly sensitive to excess adiposity in children. These findings extend previous work implicating adiposity in cognitive health in the pediatric population.Study importance1.What is already known about this subject?a.Excess adiposity is inversely associated with cognitive function in children.b.Adiposity has been associated with several event-related brain potentials, such that smaller P3 components, which index stimulus evaluation, and larger N2 components, which index attentional inhibition, are related to greater adiposity in children.c.The neural correlates underlying the cognition-adiposity relationship are under specified, and additional ERP components should be studied; one such component is the LRP, which underlies motor planning and activation.2.What does your study add?a.Our results show that adiposity was related to the P3 and the response-locked LRP components such that children with less adiposity showed larger P3 and LRP waveforms.b.These findings suggest that two separable, though related, processes may be affected by adiposity in childhood: One involving the evaluation of a stimulus, represented by the P3, and one involving the activation of motor control, represented by the response-locked LRP.Clinical Registry Number: NCT02630667 at https://clinicaltrials.gov.
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research