Effects of Intermittent Hypoxia on Expression of Glucose Metabolism Genes in MCF7 Breast Cancer Cell line.

CONCLUSION: It is concluded, from this study, that 30 intermitted hypoxic episodes increased the survival rate of MCF7 breast cancer cells and induced Warburg effect through upregulation the expression of genes involved in the glycolysis pathway. These results may increase our understanding of the molecular alterations of breast cancer cells under hypoxic condition.
PMID: 31738135 [PubMed - as supplied by publisher]

Source: Current Cancer Drug Targets - November 14, 2019 Category: Cancer & Oncology Authors: Jarrar Y, Zihlif M, Bawab A, Sharab A Tags: Curr Cancer Drug Targets Source Type: research