A Case of a Pregnant Patient on Hemodialysis who Showed Remarkable Improvement of Severe Hyperparathyroidism by Strict Serum Phosphorus Control.

A Case of a Pregnant Patient on Hemodialysis who Showed Remarkable Improvement of Severe Hyperparathyroidism by Strict Serum Phosphorus Control. Intern Med. 2019 Nov 18;: Authors: Ito J, Fujii H, Kono K, Goto S, Nishi S Abstract We encountered a pregnant hemodialysis patient with severe hyperparathyroidism (HPT). Although her disease was considered to be refractory to medical treatment, the serum intact parathyroid hormone (PTH) level remarkably improved without manifestation of hypercalcemia through only strict serum phosphorus control, mainly via intensification of dialysis. The very strong correlation between the serum phosphorus level and serum intact PTH level suggested the possibility of secondary HPT. She ultimately gave birth to a healthy baby. The clinical course of the patient's HPT and the growth of the child have been good for more than six years. PMID: 31735793 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research

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ConclusionThe prevalence of gestational PHPT was 2.1% in this largest Indian PHPT cohort, which is higher than that reported from the West (
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
CONCLUSION: In absence of guidelines for GPHPT management, its treatment should be individualized. In our case, despite high calcium levels, a conservative treatment with strict monitoring led to positive outcome of pregnancy. PMID: 33030137 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Endocrinology Authors: Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
CONCLUSION: Rates of perinatal complications in our series are more reassuring than the ubiquitously quoted rates from small and dated studies. The diagnosis of primary hyperparathyroidism may be easily missed during pregnancy, owing to its non-specific presentation. A high index of suspicion and measurement of ionized calcium levels is encouraged, especially for patients with excessive nausea and vomiting, nephrolithiasis, atypical presentations of hypertensive disorders, or isolated polyhydramnios. Mild degrees of calcium derangement do not preclude adverse perinatal outcomes. Surgery appears to be safe, even in the thir...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
In conclusion, most common causes of hypercalcemia were excluded in the majority of women. Hypercalcemic women had a relatively high serum 1,25(OH)2D concentration despite an appropriately suppressed PTH, suggestive of abnormal gestational adaptions.
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
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Source: Gynecological Endocrinology - Category: Endocrinology Authors: Source Type: research
Mizel Tavarez, 39, was diagnosed with hyperparathyroidism, causing her body to overproduce calcium and putting her at risk of miscarriage until a risky operation fixed the glands.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Pregnancy is rare in women on hemodialysis. Recommendations for the treatment of secondary hyperparathyroidism (sHPT) and preservation of bone health in pregnant dialysis patients are lacking.
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Case report Source Type: research
Endocrine Practice,Volume 25, Issue 11, Page 1127-1136, November 2019.
Source: Endocrine Practice - Category: Endocrinology Authors: Source Type: research
Endocrine Practice,Volume 25, Issue 11, Page 1127-1136, November 2019.
Source: Endocrine Practice - Category: Endocrinology Authors: Source Type: research
Conclusions: Parathyroidectomy in primary hyperparathyroidism during pregnancy is safe. PMID: 31501633 [PubMed - in process]
Source: Cirugia y Cirujanos - Category: Surgery Authors: Tags: Cir Cir Source Type: research
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