Hemodynamic Validation of the E/e ’ Ratio as a Measure of Left Ventricular Filling Pressure in Patients with Non-ST Elevation Myocardial Infarction

The E/e ’ ratio has an established role in the assessment of left ventricular filling pressure (LVFP) in stable patients, but its accuracy in acute myocardial ischemia is less well established. The aim of this study was to validate the relationship between the E/e’ ratio and invasively measured LVFP in patients with non-ST elevation myocardial infarction (NSTEMI). A total of 120 unselected patients with NSTEMI underwent cardiac catheterization with measurement of left ventricular end-diastolic pressure (LVEDP; elevated ≥15mmHg) and Doppler echocardiography with either simultaneous (n=30) or same -day (n=90) measurement of E/e’.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research