The limits of generalizability: Why good theory can have bad outcomes
Publication date: Available online 18 November 2019Source: TechnovationAuthor(s): Jonathan D. LintonAbstractGeneralizability is the goal for scientists (both social and natural). In the social sciences invoking generalizability is more problematic as it is often based on assessment of a mainstream population, but may not apply to groups outside of the mainstream. This is a significant challenge to developing appropriate policy and interventions suitable for Other groups. An example is given of how this concern was overcome through consideration of the Voice Of the Customer (VOC) and utilizing cognitive maps to consider the challenge of diabetes in two Canadian First Nations Communities. An understanding of the limits to generalizability is important in cases where cultural, geographical, or political differences exist. This is not only an important consideration for practitioners in search of successful interventions, but also academics trying to understand and contribute to knowledge in a variety of fields; including the diffusion and adoption of innovation.
Authors: Morita K, Wang D, Baba R, Morimoto H, Song Y, Kanazawa T, Yoshida Y Abstract Although it is known that desert dust exacerbates allergic diseases, how it affects the onset of autoimmune diseases is unclear. No epidemiological investigations or animal experiments have been conducted so far to elucidate the effects of desert dust on autoimmune diseases. Here, we focused on particulate matter, such Asian sand dust (ASD) that has been known to cause adverse health effects in East Asian countries, and conducted animal experiments to examine how ASD influences type 1 diabetes (T1D), an autoimmune disease. An ASD ...
Condition: Bile Acid, Microbiota, Treatment of Diabetes Intervention: Sponsor: Chang Gung Memorial Hospital Not yet recruiting
Conditions: Ketosis; Type 2 Diabetes Interventions: Dietary Supplement: Ketone monoester; Dietary Supplement: Placebo Sponsor: University of British Columbia Recruiting
Condition: Type 2 Diabetes Mellitus Interventions: Drug: Dapagliflozin Pill; Drug: Empagliflozin Pill; Drug: Placebo pill Sponsor: Centro Universitario de Ciencias de la Salud, Mexico Not yet recruiting
Antioxidants&Redox Signaling,Volume 32, Issue 1, Page 60-77, January 1, 2020.
Publication date: Available online 11 December 2019Source: International Journal of Nursing SciencesAuthor(s): Lei Cui, Weixia Chen, Xingxing Yu, Changping JuAbstractPurposePatients undergoing maintenance hemodialysis (MHD) have a higher prevalence of cognitive impairment and inferior cognitive performance than the general population, and those with cognitive impairment are at higher risk of death than those without cognitive impairment. Having diabetes has been associated with an increased risk of cognitive decline in end-stage kidney disease patients treated with peritoneal dialysis or kidney transplant. However, these f...
Conclusions: Compared with placebo, ghrelin agonists are effective and well-tolerated for the treatment of DG. PMID: 31816671 [PubMed - as supplied by publisher]
CONCLUSIONS: This study, in line with previous studies, shows that a diagnosis of T1DM is associated with a decreased risk of schizophrenia. This finding of an inverse association between T1DM and schizophrenia may bring an interesting piece, related to autoimmunity, into the schizophrenia-aetiology puzzle. PMID: 31816222 [PubMed - as supplied by publisher]
Type 2 diabetes requires careful monitoring to reduce the risk of blood sugar spikes, which can lead to a host of health problems. Diet plays an essential role in regulating blood sugar and warding off serious threats and evidence backs regularly drinking a certain a certain tea to keep the condition in check.
Pancreas-kidney transplant extends life expectancy for patients with type 1 diabetes and renal disease more than kidney transplantation alone, according to a study published inDiabetes Care.Healio