Maternal diabetes induces autism-like behavior by hyperglycemia-mediated persistent oxidative stress and suppression of superoxide dismutase 2 [Neuroscience]

Epidemiological studies show that maternal diabetes is associated with an increased risk of autism spectrum disorders (ASDs), although the detailed mechanisms remain unclear. The present study aims to investigate the potential effect of maternal diabetes on autism-like behavior in offspring. The results of in vitro study showed that transient hyperglycemia...

Source: Proceedings of the National Academy of Sciences - November 18, 2019 Category: Science Authors: Xiumin Wang, Jianping Lu, Weiguo Xie, Xiaoyun Lu, Yujie Liang, Min Li, Zichen Wang, Xiaodong Huang, Mingxi Tang, Donald W. Pfaff, Ya-Ping Tang, Paul Yao Tags: Biological Sciences Source Type: research