Associations Between Apparent Diffusion Coefficient Values and the Prognostic Factors of Breast Cancer

Conclusions Apparent diffusion coefficient values were shown to be correlated with many proven or possible prognostic factors of breast cancer. In particular, ADCdiff can reflect tumor heterogeneity and showed higher correlation.
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Breast Imaging Source Type: research

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(ECOG-ACRIN Cancer Research Group) According to a study published today in the Journal of the American Medical Association, when screening women at average risk with dense breast tissue, abbreviated breast magnetic resonance imaging (MRI) detected significantly more cancers (almost two and a half times as many) than digital breast tomosynthesis (3D mammography). The study compared the 10-minute MRI exam to 3D mammography, in women with dense breasts, because the ability of mammography to detect breast cancer is limited in these women.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
China has an increasing burden of breast cancer, but with a population of dense breast patients, the diagnostic efficiency of conventional digital mammography was attenuated. Our study suggested that CESM exhibited an excellent diagnostic efficiency and a moderate correlation in lesion size estimation compared to DCE ‐MRI and pathology, supporting it to be an alternative to DCE‐MRI in breast cancer detection and diagnosis, especially for exclusion diagnosis in dense breast patients. AbstractBackgroundChina has an increasing burden of breast cancer. However, with a large population of dense breast patients, the diagnost...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This randomized trial compares the accuracy of screening with abbreviated breast magnetic resonance imaging (MRI) vs digital breast tomosynthesis (DBT) on invasive breast cancer detection rates in women with dense breasts.
Source: JAMA - Category: General Medicine Source Type: research
ConclusionsUS may underestimate breast tumor size. Treatment decisions that take into account tumor size can be made equally reliably in patients with high or low breast density.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionsApplying the Kaiser score to breast MRI allows stratifying the risk of breast cancer in lesions that present as suspicious calcifications on mammography and may thus avoid unnecessary breast biopsies.Key Points• The Kaiser score is a helpful clinical decision tool for distinguishing malignant from benign breast lesions that present as calcifications on mammography.• Application of the Kaiser score may obviate 58.3–65.3% of unnecessary stereotactic biopsies of suspicious calcifications.• High Kaiser scores predict breast cancer with high specificity, aiding clinical decision-making with regar...
Source: European Radiology - Category: Radiology Source Type: research
AbstractPurpose of ReviewWe review the management for unaffectedBRCA1/2 mutation carriers and the local management of early-stage breast cancer.Recent FindingsFor unaffectedBRCA1/2 mutation carriers, surveillance includes annual magnetic resonance imaging (MRI) and mammogram (MG). Novel imaging modalities, including abbreviated protocol MRI, ultrafast/accelerated MRI, and contrast-enhanced digital mammography are being investigated. Risk-reducing mastectomy (RRM) should be considered, and nipple-areolar sparing mastectomy (NSM) is now an option. Additionally, risk-reducing salpingo-oophorectomy (RRSO) is strongly recommend...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
ConclusionPharmacokinetic quantitative parameters with histogram and texture features obtained from DCE-MRI are associated with the molecular subtypes of breast cancer, and may serve as potential imaging biomarkers to differentiate between the luminal A and luminal B molecular subtypes.
Source: Academic Radiology - Category: Radiology Source Type: research
ConclusionsIn patients with TNBC-NST, intra-E and intra-N did not correlate with pCR, but intra-E did positively correlate with tumor size. NST may exhibit a greater response to NAC, regardless of whether intra-E or intra-N is present or not on the pretreatment MRI.Key Points• Pathological complete response in TNBC-NST had no correlation with intramammary edema or intratumoral necrosis.• NAC may be justified in TNBC-NST even in the presence of edema or necrosis.• The extension of edema correlated with tumor size of TNBC-NST.
Source: European Radiology - Category: Radiology Source Type: research
Conclusion: Our results indicated that DCE-MRI could be considered an important auxiliary method for evaluating the pathological response of breast cancer to NAC and used as an effective method for dynamically monitoring the efficacy during NAC. DCE-MRI also performed well in predicting the pCR of breast cancer to NAC. However, due to the heterogeneity of the included studies, caution should be exercised in applying our results.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
AbstractBackground and purposeMultiparametric radiological imaging is vital for detection, characterization, and diagnosis of many different diseases. Radiomics provide quantitative metrics from radiological imaging that may infer potential biological meaning of the underlying tissue. However, current methods are limited to regions of interest extracted from a single imaging parameter or modality, which limits the amount of information available within the data. This limitation can directly affect the integration and applicable scope of radiomics into different clinical settings, since single image radiomics are not capabl...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
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