Accuracy of Pulmonary Nodule Volumetry at Different Exposure Parameters in Low-Dose Computed Tomography: A Phantom Study

Objective To explore the exposure parameters with minimized radiation dose for accurate pulmonary nodule volumetry using low-dose computed tomography (LDCT). Methods An anthropomorphic chest phantom with 11 pulmonary nodules (6 solid nodules and 5 ground-glass opacities) was scanned using 256-slice multidetector computed tomography scanner at various tube voltage and current (combinations of 80, 100 and 120 kV with 10 to 30 mAs). Raw data sets were reconstructed using the hybrid iterative reconstruction method and nodule volume was calculated by a semiautomatic software. The absolute percentage error (APE) of nodule volume relating to the reference acquisition and contrast-to-noise ratio was measured. Results Nodule characteristic and tube voltage (P
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Cardiothoracic Imaging Source Type: research