Neuroprotective Role of Dexmedetomidine in Epilepsy Surgery

Claudia Nino, Jose D Mercado, Natalia Cabrera, Carlos I QuinteroNeurology India 2019 67(5):1363-1363
Source: Neurology India - Category: Neurology Authors: Source Type: research

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Publication date: January 2020Source: The Lancet Neurology, Volume 19, Issue 1Author(s): Page B Pennell
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: January 2020Source: Epilepsy &Behavior, Volume 102Author(s): Soha Alomar, Mai Kadi, Doaa Alabbas, Mohammed Aljeddawi, Sama Alsulaiman, Saleh Baeesa, Abdulrahman SabbaghAbstractPurposeEpilepsy affects individuals of all ages and genders and places high physical, mental, financial, and social burdens on these individuals. In Saudi Arabia, its prevalence is 6.5 cases per 1000 individuals. Physicians and healthcare professionals have a key role in increasing the knowledge and awareness of the general population about epilepsy. The purpose of this study was to assess the level of awareness of different asp...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
C, Ramos-Clason E Abstract AIM: To determine feasibility, reliability and validity of the shortened version of the Quality of Life in Epilepsy Inventory-10 (QOLIE-10) in a population of refractory epilepsy adult patients in the Colombian Caribbean. PATIENTS AND METHODS: Data were collected from 63 adult refractory epilepsy patients. The ten items of QOLIE-10 were derived from the Spanish version of QOLIE-89. We assess feasibility, validity, factorial analysis with communalities, reliability through internal consistency and sensitivity to change. RESULTS: Clinical and demographic features were determined;...
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
Publication date: Available online 11 December 2019Source: Neurochemistry InternationalAuthor(s): Kuo Zhang, Fan Wang, Yang Zhao, Meiyao He, Yuanchao Luo, Yue Cheng, Jing Luo, Zhimei Li, Jingyu YangAbstractAdult hippocampal neurogenesis plays the pivotal roles in central nervous system diseases. Recently, it has been reported that levetiracetam (LEV), a new antiepileptic drug with novel chemical construction and unique pharmacological properties, suppressed aberrant adult subventricular zone (SGZ) neurogenesis in kainite-induced epileptic mice, while promoted adult SGZ neuroblast differentiation in normal mice. These studi...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
Epilepsy should be suspected in patients with Stiff ‐person syndrome and new onset paroxysmal episodes. Musicogenic epilepsy may be a manifestation of anti‐GAD‐Ab spectrum, supporting an autoimmune workup in these patients. Appropriate treatment is not well established, and immunotherapy should be considered in patients with only partial respon se to antiepileptic drugs. AbstractEpilepsy should be suspected in patients with Stiff ‐person syndrome and new onset paroxysmal episodes. Musicogenic epilepsy may be a manifestation of anti‐GAD‐Ab spectrum, supporting an autoimmune workup in these patients. Appropriate ...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
Publication date: March 2020Source: Biomedical Signal Processing and Control, Volume 57Author(s): Susanta Kumar Rout, Pradyut Kumar BiswalAbstractIn this paper, variational mode decomposition (VMD), Hilbert transform (HT), and proposed error-minimized random vector functional link network (EMRVFLN) are integrated to detect and classify epileptic seizure from electroencephalogram (EEG) signals. VMD is applied to decompose the EEG signal into Band-limited intrinsic mode functions (BLIMFs). The five efficacious instantaneous features are computed using HT to construct the feature vector. Proposed EMRVFLN classifier is used to...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Authors: Kavčič A, Kajdič N, Rener-Primec Z, Krajnc N, Žgur T Abstract To review the outcome of vagus nerve stimulation (VNS) therapy in all implanted Slovenian patients with drug-resistant epilepsy, data on 48 patients implanted between 2001 and 2015 were obtained retrospectively from medical records. The outcome was assessed in 2016. Out of 48 patients, 39 responded at follow up. The seizure frequency was reduced in 18 (46.2%) patients; 13 (33.3%) of them reported ≥50% reduction after 12 months of therapy. The responder rate was higher among patients implanted before the age of six years. Ictal severity de...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
Marinus Pharmaceuticals Inc. expects to bring in $65 million this week from a public stock offering and concurrent private placement. The proceeds from the stock sales will be used by the Radnor company to advance the preclinical and clinical development of ganaxolone, its lead new drug candidate. Marinus is developing ganaxolone as a potential treatment for epilepsy, depression and other neuropsychiatric disorders. The funds wi ll be used for clinical trial expenses related to the company's seizure…
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
In the first study of its kind, investigators, using AI, found that young epilepsy patients were more than twice as likely as adults with epilepsy to discuss suicidal thoughts and behaviors online.Medscape Medical News
Source: Medscape Pediatrics Headlines - Category: Pediatrics Tags: Neurology & Neurosurgery News Source Type: news
Publication date: December 2019Source: Seizure, Volume 73Author(s): Sang-Ahm Lee
Source: Seizure - Category: Neurology Source Type: research
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