Biomarker-Based Prediction of Progression to Dementia: F-18 FDG-PET in Amnestic MCI

Conclusion: FDG-PET-based visual and cortex ID classification has a good accuracy in predicting progression to dementia including AD in the prodromal aMCI phase. Absence of typical metabolic patterns on FDG-PET can play an important exclusionary role for progression to dementia. Vascular cognitive impairment with cerebral atrophy needs further studies to confirm and uncover potential mechanisms.

http://www.neurologyindia.com/text.asp?2019/67/5/1310/271245

Source: Neurology India - November 18, 2019 Category: Neurology Authors: Madhavi Tripathi Manjari Tripathi Girish Kumar Parida Rajeev Kumar Sadanand Dwivedi Ashima Nehra Chandrasekhar Bal Source Type: research