Predictors of the trajectory of cognitive functioning in the first 6 months after allogeneic hematopoietic stem cell transplantation
Bone Marrow Transplantation, Published online: 19 November 2019; doi:10.1038/s41409-019-0746-3Predictors of the trajectory of cognitive functioning in the first 6 months after allogeneic hematopoietic stem cell transplantation
Bone Marrow Transplantation, Published online: 10 December 2019; doi:10.1038/s41409-019-0772-1Oral verruciform xanthoma associated with stem cell transplantation and graft versus host disease in a paediatric patient
Bone Marrow Transplantation, Published online: 10 December 2019; doi:10.1038/s41409-019-0770-3Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant
Bone Marrow Transplantation, Published online: 09 December 2019; doi:10.1038/s41409-019-0765-0Clinical course of autologous recovery with chromosomal abnormalities after allogeneic hematopoietic stem cell transplantation
Abstract Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a chronic autoimmune disease involving the peripheral nervous system, characterized by focal and segmental demyelination accounting for neurological deficit. CIDP diagnosis is based on several criteria and requires the presence of specific clinical symptoms and of demyelinating criteria on the electroneuromyogram (ENMG) or of additional supportive criteria (spinal fluid examination with dissociation between albumin level and cellular abnormalities, nervous abnormalities on MRI or other minor abnormalities on ENMG, demyelinating features on nerve ...
Bone Marrow Transplantation, Published online: 05 December 2019; doi:10.1038/s41409-019-0766-zPDGFB-expressing mesenchymal stem cells improve human hematopoietic stem cell engraftment in immunodeficient mice
In this study, we have evaluated the role of ROS in GVHD pathogenesis by treatment of recipient mice with apocynin (apo), an inhibitor of intracellular translocation of cytosolic components of NADPH oxidase complex. The pharmacological blockade of NADPH oxidase resulted in prolonged survival and reduced GVHD clinical score. This reduction in GVHD was associated with reduced levels of ROS and TBARS in target organs of GVHD in apocynin-treated mice at the onset of the mortality phase. These results correlated with reduced intestinal and liver injuries and decreased levels of proinflammatory cytokines and chemokines. Mechanis...
Bone Marrow Transplantation, Published online: 29 November 2019; doi:10.1038/s41409-019-0761-4HLA-mismatched microtransplantation for relapsed or refractory acute myeloid leukemia as a bridge to allogeneic hematopoietic stem cell transplantation
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In astudy published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions.Multiplying blood stem cells in conditions outside the human body could greatly improve treatment options for blood cancers like leukemia and for many inherited blood diseases.Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and senior author of the study, h...
Bone Marrow Transplantation, Published online: 26 November 2019; doi:10.1038/s41409-019-0760-5Pretransplantation vitamin A plasma levels and risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
Bone Marrow Transplantation, Published online: 25 November 2019; doi:10.1038/s41409-019-0756-1The timing of plerixafor addition to G-Csf and chemotherapy affects immunological recovery after autologous stem cell transplant in multiple myeloma