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Hepatic Encephalopathy
Source: Clinics in Liver Disease - Category: Gastroenterology Source Type: research

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Conclusion: Our study demonstrated the urgent need for improved liver screening, health education regarding risk behavior and improved awareness campaigns on liver disease. Interest of the general population may be presumed as more than 200,000 people accessed our test of their own accord. PMID: 31822163 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
ConclusionsLiver organoid model recapitulates the key features of Z-AAT deficiency and provides a useful tool for disease modeling.
Source: Hepatology International - Category: Infectious Diseases Source Type: research
Hepatocellular carcinoma (HCC) ranks among the most rapidly evolving cancers in the Western world. The majority of HCCs develop on the basis of a chronic inflammatory liver damage that predisposes liver cancer development and leads to deregulation of multiple cellular signaling pathways. The resulting dysbalance between uncontrolled proliferation and impaired predisposition to cell death with consecutive failure to clear inflammatory damage is a key driver of malignant transformation. Therefore, resistance to death signaling accompanied by metabolic changes as well as failed immunological clearance of damaged pre-neoplasti...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Blood tests can usually show whether a person has hepatitis C. However, these tests can give false-positive readings. Here, learn why this can happen.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news
This study aimed to assess the association between serum ferritin (SF) and NAFLD among middle-aged and elderly Chinese with normal weight. METHODS AND STUDY DESIGN: A total of 2029 Chinese adults aged 35-70 years with normal weight were involved in this cross-sectional study. General information, lifestyle factors and laboratory characteristics were collected. The concentrations of serum alanine aminotransferase (ALT) and SF were recorded. Receiver operating characteristic (ROC) was applied to assess predictive performance of SF for NAFLD. Logistic regression analysis was conducted to evaluate the associations of SF w...
Source: Asia Pacific Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Asia Pac J Clin Nutr Source Type: research
(Natural News) It cannot be stressed enough that physical activity, such as walking and working out, is vital for improving overall health. Now, a recent study suggests that physical activity can significantly benefit people suffering from liver disease. The study, presented at Digestive Disease Week 2019, found that physical activity was linked to a significant reduction in the...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
(Natural News) Extracts from the medicinal mushroom Cordyceps militaris can potentially be used to prevent — even reverse — nonalcoholic fatty liver disease (NAFLD), one of the most prevalent forms of liver disease among American adults. In a study published in the Journal of Medicinal Food, researchers from South Korea investigated whether C. militaris can regulate lipogenesis in the...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
During chronic liver disease, macrophages support angiogenesis, not only by secreting proangiogenic growth factors and matrix-remodeling proteases, but also by physically interacting with the sprouting vasculature to assist the formation of complex vascular networks. In the liver, macrophages acquire specific characteristics becoming Kupffer cells and working to ensure protection and immunotolerance. Angiogenesis is another double-edged sword in health and disease and it is the biggest ally of macrophages allowing its dissemination. Angiogenesis and fibrosis may occur in parallel in several tissues as macrophages co-locali...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Obesity is a prevalent predisposing factor to non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in the developed world. NAFLD spectrum of disease involves progression from steatosis (NAFL), to steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). Despite clinical and public health significance, current FDA approved therapies for NAFLD are lacking in part due to insufficient understanding of pathogenic mechanisms driving disease progression. The etiology of NAFLD is multifactorial. The induction of both systemic and tissue inflammation consequential of skewed immune cell metabo...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Cardiometabolic diseases encompass those affecting the heart and vasculature as well as other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver disease. These diseases tend to have common risk factors, one of which is impaired adiponectin action. This may be due to reduced bioavailability of the hormone or resistance to its effects on target tissues. A strong negative correlation between adiponectin levels and cardiometabolic diseases has been well-documented and research shown that adiponectin has cardioprotective, insulin sensitizing and direct beneficial metabolic effects. Thus, the...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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