Modelling the optimal target age group for seasonal influenza vaccination in Japan.

CONCLUSIONS: A vaccination programme which targets children under 15 is predicted to have much larger epidemiological impact than those targeting elderly. PMID: 31735503 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research

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While the world awaits a proven COVID-19 vaccine, medical experts are turning their attention to a shot that’s long been a key component in the public health toolbox: the flu vaccine. Experts hope this year’s flu shot can help prevent an influenza epidemic paired with another wave of coronavirus, which could overwhelm hospitals and lead to general confusion, given that it can be difficult to tell a COVID-19 infection from a case of the flu. This flu season is also something of a dress rehearsal for the eventual rollout of a COVID-19 vaccine amid the ongoing pandemic, allowing doctors, nurses and pharmacists a c...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
"Pediatric vaccination will be an important component to mitigating a dual influenza/COVID-19 epidemic."Medscape Medical News
Source: Medscape Internal Medicine Headlines - Category: Internal Medicine Tags: Pediatrics News Source Type: news
An influenza epidemic alongside the ongoing COVID-19 pandemic -- it's the "twindemic" that health officials are trying to avoid. Dr. Gregory Poland, a Mayo Clinic vaccine expert, explains why getting a flu vaccination is so important. Watch: The Mayo Clinic Minute https://youtu.be/RnxmIRevkZE Journalists: Broadcast-quality video (0:59) is in the downloads at the end of this [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
We present advances in modeling techniques that have led to fundamental disease discoveries and impacted clinical translation.Recent FindingsCombining mechanistic models and machine learning algorithms has led to improvements in the treatment ofShigella and tuberculosis through the development of novel compounds. Modeling of the epidemic dynamics of malaria at the within-host and between-host level has afforded the development of more effective vaccination and antimalarial therapies. Similarly, in-host and host-host models have supported the development of new HIV treatment modalities and an improved understanding of the i...
Source: Current Pathobiology Reports - Category: Laboratory Medicine Source Type: research
CONCLUSIONS: Influenza type B has a higher incidence in the paediatric population and type A affects more the adult population. Only 28.8% of patients with Influenza B that presented with some underlying condition or risk factor were vaccinated. This shows the need to increase coverage with tetravalent vaccines in order to reduce the burden of disease associated with the Influenza B virus. PMID: 32957746 [PubMed - as supplied by publisher]
Source: Revista Espanola de Quimioterapia - Category: Drugs & Pharmacology Authors: Tags: Rev Esp Quimioter Source Type: research
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Errata Source Type: research
r U Abstract For a long time, most of the infectious diseases seemed to have become under control. In particular, vaccinations have contributed to this development. In recent years newly occurring bacterial infections caused by multidrug-resistant pathogens and viral infections, such as the chikungunya virus, influenza epidemics and currently the COVID-19 pandemic, are endangering the world population. This specifically affects patients with rheumatological diseases, who often require immunosuppressive therapy and are thus at risk for infections. Vaccinations can protect those affected, both individually and ...
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research
In this study, we addressed the issue of a vitamin D modulatory effect on the immune response to seasonal influenza vaccination in elderly persons. The study comprised 96 participants aged 60-75 during the 2016/17 epidemic season. After the determination of the baseline content of VIT D and anti-hemagglutinin antibodies (H1, H3, and HB), participants were vaccinated with a trivalent vaccine. The content of the anti-hemagglutinin antibodies was rechecked 4-5 weeks afterward, showing inappreciable alterations. The negative findings of this study make the influence of serum VIT D content on the immunogenicity of influenz...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
This article reviews the progress in development of universal vaccines directed against the conserved regions of hemagglutinin (HA), neuraminidase (NA), and other structural proteins of influenza viruses using new technologies and strategies with the goals of enhancing our understanding of universal influenza vaccines and providing a reference for research into the exploitation of natural immunity against influenza viruses.
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
ns JA Abstract COVID-19 has been disturbing human society with an intensity never seen since the Influenza epidemic (Spanish flu). COVID-19 and Influenza are both respiratory viruses and, in this study, we explore the relations of COVID-19 and Influenza with atmospheric variables and socio-economic conditions for tropical and subtropical climates in Brazil. Atmospheric variables, mobility, socio-economic conditions and population information were analyzed using a generalized additive model for daily COVID-19 cases from March 1st to May 15th, 2020, and for daily Influenza hospitalizations (2017-2019) in Brazilian s...
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
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