Facile biofabrication, characterization, evaluation of photocatalytic, antipathogenic activity and in vitro cytotoxicity of zinc oxide nanoparticles

In this study, the obtained IC50 concentration of 51.25 μg/mL exhibits significant anticancer activity against A549 cells than other tested concentrations because of the release of zinc ions, which induce the cell apoptosis. Furthermore, studies on cell cycle validate that ZnO NPs arrest the cell cycle at the sub-G1 phase of A549 cells. These results suggest the utility of phytogenic ZnO NPs for various biomedical applications.Graphical abstract
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research

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In this study we explored the use of a natural compound rubusoside (RUB) as a solubilizer to enhance the solubility of a fluorescence-labeled C6-Ceramide (NBD C6-Ceramide) and to characterize its pharmacokinetics and tissue distribution in an animal model. RUB significantly enhanced the solubility of NBD C6-Ceramide by forming nanomicelles, and efficiently delivered NBD C6-Ceramide in rats by oral and intravenous administration. RUB loaded 1.96% of NBD C6-Ceramide in the nanomicelles and solubilized it to a concentration of 3.6 mg/mL in water. NBD C6-Ceramide in nanomicelles remained stable in aqueous solutions, all...
Source: Prostaglandins and Other Lipid Mediators - Category: Lipidology Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Food Composition and AnalysisAuthor(s): Afsaneh Mohajer, Abbas Norouzian Baghani, Parisa Sadighara, Kiandokht Ghanati, Shahrokh NazmaraAbstractIn this current study, the contents of heavy metals including Pb, As, Cr, Cd, Zn, Cu, and Mn in imported rice bran oil in Iran were investigated with microwave digestion method based on an inductively coupled plasma optical emission spectrometry system (ICP-OES). The concentrations range of Pb, Cr, Cd, As, Zn, and Cu in rice bran oil samples were measured as 0.066 - 0.30, 0.008 - 0.014, 0.005 - 0.01, 0.047- 0.01, ...
Source: Journal of Food Composition and Analysis - Category: Food Science Source Type: research
In this study, the effects of the addition of various polysaccharides (konjac gum, gellan gum, and curdlan gum) on the rheological and textural properties of calcium sulfate-induced soy protein isolate gels were investigated. The incorporation of konjac gum and curdlan gum at 0.3 and 0.5% (w/v) concentrations and gellan gum at 0.5% concentration significantly enhanced (P 
Source: Food Chemistry - Category: Food Science Source Type: research
Authors: Hill BG, Shiva S, Ballinger S, Zhang J, Darley-Usmar VM Abstract It is now becoming clear that human metabolism is extremely plastic and varies substantially between healthy individuals. Understanding the biochemistry that underlies this physiology will enable personalized clinical interventions related to metabolism. Mitochondrial quality control and the detailed mechanisms of mitochondrial energy generation are central to understanding susceptibility to pathologies associated with aging including cancer, cardiac and neurodegenerative diseases. A precision medicine approach is also needed to evaluate the ...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
Publication date: Available online 10 December 2019Source: Artificial Intelligence in MedicineAuthor(s): Sarah Ali Abdelaziz Ismael, Ammar Mohammed, Hesham HefnyAbstractCancer is the second leading cause of death after cardiovascular diseases. Out of all types of cancer, brain cancer has the lowest survival rate. Brain tumors can have different types depending on their shape, texture, and location. Proper diagnosis of the tumor type enables the doctor to make the correct treatment choice and help save the patient's life. There is a high need in the Artificial Intelligence field for a Computer Assisted Diagnosis (CAD) syste...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
Diagnostic accuracy of troponin T measured ≥6h after symptom onset for ruling out myocardial infarction. Scand Cardiovasc J. 2019 Dec 09;:1-9 Authors: Khoshnood A, Erlandsson M, Isma N, Yndigegn T, Mokhtari A Abstract Objectives: Guidelines recommend a single high-sensitivity cardiac troponin T (hs-cTnT) ≤14 ng/L measured ≥6 h after chest pain onset combined with a GRACE score
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Publication date: Available online 11 December 2019Source: Results in PhysicsAuthor(s): Biao Zheng, Cheng Zhang, Chunlei Huang, Jinquan Hong, Yuliang Li, Jun Wang, Lin Lin, Zhiqiang ZhengAbstractMultifunctional NiO@Gd2O3:Er3+,Yb3+ hollow nanocomposites (NCs) with mesoporous, upconversion (UC) luminescent and magnetic properties are synthesized by a facile hydrothermal process. Transmission electron microscope (TEM) and scanning electron microscope (SEM) images reveal that the samples have hollow structures with double shells of UC layer and magnetic layer. N2 adsorption/ desorption isotherm analysis shows the samples have ...
Source: Results in Physics - Category: Physics Source Type: research
Publication date: Available online 7 December 2019Source: Radiation Physics and ChemistryAuthor(s): Anikó Bezsenyi, Gyuri Sági, Magdolna Makó, György Palkó, Tünde Tóth, László Wojnárovits, Erzsébet TakácsAbstractDiclofenac and sulfamethoxazole are poorly degradable when using activated sludge or biofilm biomass in biological wastewater treatment. However, a biological phenomenon called cometabolism can improve the removal efficiency, especially in activated sludge treatment. In the case of cometabolism an easily degradable substrate is added to...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Publication date: Available online 7 December 2019Source: Radiation Physics and ChemistryAuthor(s): Gregory P. Horne, Christopher A. Zarzana, Dayna L. Daubaras, Corey D. Pilgrim, Cathy Rae, Richard F. Faulkner, James J. Kiddle, Stephen P. MezykAbstractPrevious investigation into the radiation chemistry of the ligand octylphenyl-N,N-diisobutylcarbamoylmethyl phosphine oxide (CMPO) and its analogues demonstrated their ability to undergo activated radioprotection in an organic solvent – a feature most advantageous for spent nuclear fuel reprocessing scenarios. This phenomenon was dependent on these organophosphorus comp...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Publication date: Available online 6 December 2019Source: Radiation Physics and ChemistryAuthor(s): Rabia Arshad, Tanveer H. Bokhari, Kaleem K. Khosa, Ijaz A. Bhatti, Majid Munir, Mazhar Iqbal, Dure N. Iqbal, M.I. Khan, Munawar Iqbal, Arif NazirAbstractThe gamma irradiation-induced degradation of a reactive dye Reactive Blue-19 (RB-19) as a model system in aqueous media has been evaluated. The process variables such as dye initial concentration (50–150 ppm), H2O2 concentration (0.1–0.9 ml) and gamma radiation absorbed dose (1–12 kGy) were optimized to get maximum degradation. The efficiency of AOP w...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
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