GSE140627 Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes

Contributor : Maria B MonteiroSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensUsing a discovery/validation approach we investigated associations between a panel of genes selected from a transcriptomic study and the renal function decline across time in a cohort of type 1 diabetes patients.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

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Authors: Morita K, Wang D, Baba R, Morimoto H, Song Y, Kanazawa T, Yoshida Y Abstract Although it is known that desert dust exacerbates allergic diseases, how it affects the onset of autoimmune diseases is unclear. No epidemiological investigations or animal experiments have been conducted so far to elucidate the effects of desert dust on autoimmune diseases. Here, we focused on particulate matter, such Asian sand dust (ASD) that has been known to cause adverse health effects in East Asian countries, and conducted animal experiments to examine how ASD influences type 1 diabetes (T1D), an autoimmune disease. An ASD ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
CONCLUSIONS: This study, in line with previous studies, shows that a diagnosis of T1DM is associated with a decreased risk of schizophrenia. This finding of an inverse association between T1DM and schizophrenia may bring an interesting piece, related to autoimmunity, into the schizophrenia-aetiology puzzle. PMID: 31816222 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
Pancreas-kidney transplant extends life expectancy for patients with type 1 diabetes and renal disease more than kidney transplantation alone, according to a study published inDiabetes Care.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Publication date: Available online 10 December 2019Source: Canadian Journal of DiabetesAuthor(s): Antoine B.M. Clarke, Hanaa Ahsan, Jennifer Harrington, Farid H. MahmudAbstractBackgroundThe factors associated with allied healthcare professional (HCP) time spent face-to-face with patients in clinic have not been well described in type 1 diabetes (T1D) given the introduction of resource-intensive technologies and gaps in socioeconomic circumstances.ObjectiveTo evaluate clinical and social factors associated with non-physician HCP time in a pediatric T1D practice.MethodsNon-physician HCP workload data, including time spent in...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Conditions:   Type 1 Diabetes;   Hypoglycemia Interventions:   Drug: Micro-glucagon;   Drug: Mini-glucagon Sponsor:   University Hospital Inselspital, Berne Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Nephropathy;   Hypoxia;   Mitochondrial Alteration;   Type 1 Diabetes;   Autonomic Neuropathy, Diabetic Intervention:   Drug: Forxiga Sponsors:   Steno Diabetes Center Copenhagen;   Glostrup University Hospital, Copenhagen;   Novo Nordisk A/S Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Type 1 Diabetes;   Hypoglycemia Interventions:   Drug: Micro-glucagon;   Drug: Mini-glucagon Sponsor:   University Hospital Inselspital, Berne Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Funding Opportunity RFA-DK-19-028 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications for funding to perform research leading to the development of novel and supportive technologies for the improvement of cell replacement interventions using novel methods, biomaterials and devices for type 1 diabetes (T1D) treatment.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Type 1 diabetes (T1D) has been associated with a higher fracture risk due to alterations in bone structure and metabolism. On the other hand, the important role of the RANKL/OPG/RANK signaling axis in bone phy...
Source: Italian Journal of Pediatrics - Category: Pediatrics Authors: Tags: Research Source Type: research
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