microRNA ‐144 relieves chronic constriction injury‐induced neuropathic pain via targeting RASA1

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Source: Biotechnology and Applied Biochemistry - Category: Biochemistry Authors: Tags: Original Article Source Type: research

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Publication date: November 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 6Author(s): Harish Seethapathy, Lama NoureddineCalciphylaxis is a rare disorder of poor prognosis that can lead to intense, painful lesions involving the skin and subcutaneous tissue. Although mostly described in dialysis patients, it can affect patients with normal kidney function. The diagnosis of calciphylaxis is complicated by the absence of a gold standard marker of disease such as a clear histopathological finding. Late diagnosis and advanced lesions can significantly shorten life expectancy. Calciphylaxis wounds can have a ma...
Source: Advances in Chronic Kidney Disease - Category: Urology & Nephrology Source Type: research
BACKGROUND AND AIMS: Trauma is one of the most common causes of morbidity and mortality in people of working age. Following surgery, approximately 10% of patients develop persistent postsurgical pain. Chronic pain is a complex phenomenon that can adversely...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
In conclusion, the prepared LAF-loaded membrane is a novel formulation for the treatment of chronic and long-term pain.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
This study examined the prevalence of somatization disorder in Urological Chronic Pelvic Pain Syndrome (UCPPS) and the utility of two self-report symptom screening tools for assessment of somatization in patie...
Source: BMC Urology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
This article provides an overview of the advantages and limitations of these specific harm‐reduction strategies and provides guidance on how to practically utilize them when caring for patients with cancer pain.Implications for Practice.Treating cancer pain has important and unique considerations compared with other chronic, noncancer pain disorders. The use of risk mitigation strategies for opioid prescribing as promoted by the Centers for Disease Control and Prevention does not translate seamlessly to patients with cancer. It is crucial to be wary of the advantages and pitfalls of all risk mitigation strategies related...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Symptom Management and Supportive Care Cancer Care and the Opioid Crisis Source Type: research
In October 2017, the United States government declared a state of public health emergency in response to the growing prescription opioid epidemic. Social, political, and medical rhetoric has recently demanded improvements in clinical pain control, prompting the publication of the “Guideline for Prescribing Opioids for Chronic Pain” by the Centers for Disease Control and Prevention (CDC) in March, 2016.31 Over the last decade, opioid use in the US has risen dramatically, with the number of prescriptions written by health care providers in 2012 (∼259 million) exceeding t he total adult population (∼240 million).
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Review Article Source Type: research
Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment for major depressive disorder [1]. Recently, we investigated 10 sessions of high-frequency rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) in chronic stroke survivors with depression (randomised controlled trial; ACTRN12619001303134; institutional ethics approval 200697). Stimulation was delivered at 110% resting motor threshold at 10 Hz for a total of 3000 pulses. Here we report the experience of a 51-year-old male with mild upper-limb impairment (Fugl-Meyer 49/66; structural imaging Figure 1), who experienced anatomically confine...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
ConclusionGiven the increasing number of such surgeries performed the recognition of acute and chronic complications, and their optimal management is of great importance. Although performing a Roux-en-Y fistulojejunostomy was recommended in the literature, conservative and endoscopic treatment should be considered before.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Insomnia and co-existing sleeplessness and musculoskeletal pain were inversely related to long-term recovery from chronic low back pain, a study found; relieving sleep problems may improve recovery.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - Category: Primary Care Tags: Internal Medicine News Source Type: news
Condition:   Low Back Pain Interventions:   Other: Pain Neuroscience Education and gradual exposure;   Other: Pilates and postural education Sponsor:   Aveiro University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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