Gingival Epithelial Cell Recognition of Lipopolysaccharide.

This study has identified a unique LPS sensing mechanism of the oral epithelium to overcome a periodontal infection associated with LPS derived from gram-negative microbes that arises during dysbiosis. PMID: 31732934 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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Publication date: December 2019Source: The Journal of Prosthetic Dentistry, Volume 122, Issue 6Author(s): Maria Sílvia Maurício Rigolin, Paula Aboud Barbugli, Janaina Habib Jorge, Marina Rosa Delgado Reis, Gelson Luis Adabo, Luciana Assirati Casemiro, Carlos Henrique Gomes Martins, Omar José de Lima, Francisco de Assis Mollo JuniorAbstractStatement of problemThe longevity of dental implants depends on the maintenance of peri-implant tissue and absence of inflammation. How the physical-chemical properties intrinsic to each material over time can affect adhesion, given constant cell turnover and biofilm ...
Source: The Journal of Prosthetic Dentistry - Category: Dentistry Source Type: research
DNA and Cell Biology, Ahead of Print.
Source: DNA and Cell Biology - Category: Cytology Authors: Source Type: research
This report describes a rare case of acute pylephlebitis complicated by hepatic abscess formation secondary to Fusobacterium nucleatum. The patient is a 48-year-old woman who presented with worsening abdominal pain and malaise for 3 weeks. She had a Roux-en-Y gastric bypass surgery 4 months earlier that showed a phlegmon at the surgical site on a contrast computed tomography scan postsurgery. Physical examination revealed right upper quadrant tenderness, and magnetic resonance imaging of the liver showed portal vein thrombosis with multiple hepatic abscesses. The patient was started empirically on cefepime and metronidazol...
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research
A comprehensive understanding about the pathogenesis of otitis media (OM), one of the most common pediatric diseases, has the potential to alleviate a substantial disease burden across the globe. Advancements in genetic and bioinformatic detection methods, as well as a growing interest in the microbiome, has enhanced the capability of researchers to investigate the interplay between host genes, host microbiome, invading bacteria, and resulting OM susceptibility. Early studies deciphering the role of genetics in OM susceptibility assessed the heritability of the phenotype in twin and triplet studies, followed by linkage stu...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusions: An imbalance in the oral bacterial flora could be a risk factor for AE-IPF.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Idiopathic interstitial pneumonias Source Type: research
Conclusions: Together, our results may lead to new insights for prevention of RTIs and antibiotic utilization in childhood.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric respiratory infection and immun. Source Type: research
In this study, we analyzed and compared the intestinal microbiota composition of patients with idiopathic focal epilepsy (n = 30) and healthy volunteer group (n = 10) by 16s ribosomal DNA sequencing. Proteobacteria phylum was found to be higher in patients with epilepsy (25.4%) than in healthy volunteers group (1.5%). The genera of Campylobacter, Delftia, Haemophilus, Lautropia, Neisseria among Proteobacteria phylum were found to be statistically significantly higher in patients with epilepsy than in healthy volunteers (p 
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsThis study shows that the alveolar microbiota profile in BAL samples from TB and IP patients, representing infectious and non-infectious lung diseases, respectively, is characterized by decreased diversity.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsCollectively, our data expand on the so far reported inhibitory spectrum of amixicile and demonstrates that it inhibits anaerobic bacteria, including both clinical isolates and laboratory strains.Graphical abstract
Source: Journal of Oral Biosciences - Category: Biomedical Science Source Type: research
Publication date: Available online 31 October 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Miia Kontturi, Reijo Junni, Minna Kujala-Wirth, Erja Malinen, Eija Seuna, Sinikka Pelkonen, Timo Soveri, Heli SimojokiAbstractSeveral Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 2...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
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