Evaluation of Commercial Next-Generation Sequencing Bioinformatics Software Solutions

Next-generation sequencing (NGS) diagnostics continue to expand rapidly in clinical medicine. An ever-expanding menu of molecular biomarkers are deemed important for diagnostic, prognostic, and therapeutic assessment in patients. The increasing role of NGS in the clinic is driven mainly by the falling costs of sequencing. However, the data-intensive nature of NGS makes bioinformatic analysis a major challenge to many clinical laboratories. Critically needed NGS bioinformatics personnel are hard to recruit and retain in small- to mid-size clinical laboratories.

Source: Journal of Molecular Diagnostics - November 17, 2019 Category: Pathology Authors: Rama R. Gullapalli Source Type: research