Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy

Conclusions/interpretationOur results show a previously unappreciated role of adipocyteAtp7a in the regulation of ageing-related metabolic disease and identify new metallophysiologies in whole-body fat metabolism.Data availabilityThe datasets generated during the current study are available in the Genome Sequence Archive in BIG Data Center, Beijing Institute of Genomics (BIG), Chinese Academy of Sciences, under accession number CRA001769 (http://bigd.big.ac.cn/gsa).
Source: Diabetologia - Category: Endocrinology Source Type: research