Deferoxamine Protects Stromal/Stem Cells of “Lull pgm System”-Processed Lipoaspirates Against Damages Induced by Mitochondrial Respiration Inhibition

ConclusionsAdipose-derived stromal –stem cells survive the inhibition of mitochondrial respiration better if the lipoaspirate is washed using the “Lull pgm system” rather than centrifuged. Moreover, a significant contribution to cell survival can be obtained by preconditioning stromal–stem cells with deferoxamine. In a clinic al perspective, this drug could be safely administered before surgery to patients undergoing autologous fat transfer.No Level AssignedThis journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266.
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research