Optimizing Value in the Evaluation of Chronic Spontaneous Urticaria: A Cost-effectiveness Analysis

ConclusionsIn CSU the likelihood of clinical improvement from laboratory testing is very low, and testing not cost-effective. These data support recommendations to not routinely perform laboratory testing in CSU patients with otherwise normal histories and physical evaluations.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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In this study, we bring forth updates in chronic urticaria approach, with a focus on our experience with anti-IgE therapy in different forms of chronic urticaria treated at the Allergy Department of the Professor Doctor Octavian Fodor Regional Institute of Gastroenterology and Hepatology (Cluj-Napoca, Romania). PMID: 31798727 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Chronic spontaneous urticaria (CSU) is recurrent episodes of urticaria with or without angioedema for 6 weeks or longer due to unknown (nonphysical) causes.1 Although CSU tends to be self-limited in most patients, it has still been shown to markedly affect quality of life.1 The most recent data suggest a 0.5-1% prevalence of CSU in the general population.2 The trigger for CSU is often not known; but there is an association with autoimmune disease.3-5 The treatment includes up to four times (4x) standard dosing of second-generation long-acting H1 antihistamines, short-acting H1 antihistamines, H2 antihistamines, and/or leuk...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
PMID: 31805358 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
PMID: 31761014 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
Urticaria is characterized by the appearance of hives or angioedema.1 Chronic urticaria is defined by urticarial episodes that last more than 6 weeks, occurring daily or several times per week.2 Although acute urticaria is commonly associated with infections,3 most cases of chronic urticaria have no identifiable cause. Nevertheless, several reports documented chronic urticaria from infectious causes including Helicobacter pylori.4 Studies show association of upper respiratory infections, including sinusitis, with chronic urticaria with remission after antibiotic therapy.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
Introduction: In differential diagnosis of allergic diseases, such as asthma, chronic urticaria (CU) and Hymenoptera venom allergy (HVA), the complete blood count (CBC) and spirometry are one of the crucial examinations.Aims and Objectives: To assess the blood lymphocytes, monocytes, basophiles and neutrophils and spirometry parameters in patients with asthma, CU and HVA in comparison to healthy subjects.Methods: The study involved 48 patients with asthma, 19 with CU, 12 with HVA and 17 healthy individuals. Participants had a spirometry and CBC examinations performed.Results: The absolute values of neutrophils were highest...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research
Conclusions: Among the analysed groups, patients with asthma reached highest BDI score and trait and state anxiety levels. An interesting phenomenon observed in this study, which need further examination, are higher BDI scores in healthy individuals than in CU and HVA groups.This study was financially supported by a grant from Medical University of Lodz (no.564/1-000-00/564-20-026)
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research
AbstractThe European Academy of Allergy and Clinical Immunology (EAACI) supports three journals: Allergy, Paediatric Allergy and Immunology as well as Clinical and Translational Allergy. The major goals of EAACI include (i) supporting health promotion in which the  prevention of allergy and asthma plays a critical role and (ii) disseminating the knowledge of allergy to all stakeholders including the EAACI junior members. Substantial progress was made in 2018 in the identification of basic mechanisms of atopic dermatitis and urticaria and the translation of t hese mechanisms into clinics. Many large epidemiologic studi...
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
ConclusionsCSU has strong negative effects on female sexual function, especially in patients with angioedema. Additional studies on sexual health in patients with CSU are needed and should focus on the impact of effective treatment on sexual functioning.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Authried G, Prasad SC, Rasmussen ER, Bygum A Abstract Summary: A subset of patients with angioedema (AE) and urticaria has histamine releasing autoantibodies. The histamine release test (HR-test) has been used as a tool in chronic urticaria to define the autoimmune subgroup and may possibly guide the clinician to a more personalized therapy, like omalizumab and cyclosporine. The prevalence and value of positive histamine releasing autoantibodies in monosymptomatic AE is sparsely described in the literature. The purpose of this study was to report the prevalence of positive histamine releasing autoantibodie...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
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