History of premenstrual syndrome and development of postpartum depression: A systematic review and meta-analysis
ConclusionsCurrent evidence supports a significant association between history of PMS and development of PPD. Well-designed prospective studies are needed to further investigate this relationship.
CONCLUSIONS: Prenatally initiated CBT did not improve maternal symptoms or child outcomes among non-help-seeking women with antenatal depression or anxiety. Our findings are not in line with present recommendations for universal screening and treatment for antenatal depression or anxiety, and future work may include the relevance of baseline help-seeking. PMID: 31806071 [PubMed - as supplied by publisher]
Conclusionsthe present study offers additional support to the usefulness of longitudinal S100B and drug level monitoring in depressed pregnant women and in the early detection of cases at risk for short-term neurological abnormalities. Results open the way at further investigations correlating antidepressant drugs and neurobiomarkers in the maternal bloodstream.
PMID: 31796149 [PubMed - as supplied by publisher]
AbstractPurpose of ReviewWe review evidence for physical activity and yoga as interventions for depressed pregnant and postpartum women.Recent FindingsResults from existing trials have generally indicated that physical activity and yoga interventions are acceptable to women during the perinatal period, and that these interventions can be effective in reducing depression. However, some studies have not found significant differences between intervention and control conditions. In addition, symptom improvements were not always maintained.SummaryThe available research on physical activity and yoga as interventions for perinata...
Conditions: Prenatal Anxiety; Generalized Anxiety; Postpartum Depression; Major Depressive Disorder Intervention: Behavioral: Online Cognitive Behavioural Therapy Sponsors: University of Zurich; Ambulatorium für kognitive Verhaltenstherapie und Verhaltensmedizin - UZH; Lamprecht AG Not yet recruiting
By AMEYA KULKARNI, MD When Samuel Morse left his New Haven home to paint a portrait of the Maquis du Lafayette in Washington DC, it was the last time he would see his pregnant wife. Shortly after his arrival in Washington, his wife developed complications during childbirth. A messenger took several days on horseback to relay the message to Mr Morse. Because the trip back to New Haven took several more, his wife had died by the time he arrived at their home. So moved was he by the tragedy of lost time that he dedicated the majority of the rest of his life to make sure that this would never happen to anyone again. H...
CONCLUSIONS: The male fetal-placental unit appears to be more sensitive to maternal inflammation than females. Effects are particularly marked on cerebral inhibition. Deficits in cerebral inhibition 1 month after birth, similar to those observed in several mental illnesses, including schizophrenia, indicate fetal developmental pathways that may lead to later mental illness. Deficits in early infant behavior follow. Early intervention before birth, including prenatal vitamins, folate, and choline supplements, may help prevent fetal development of pathophysiological deficits that can have life-long consequences for mental he...
DiscussionThe findings of this systematic review and meta-analysis will have both clinical and political importance in the context of perinatal mental health. In addition, this study will promote future studies and clarify the direction of research on universal prevention of perinatal depression.Systematic review registrationPROSPEROCRD42019118041
CONCLUSION: Disability to modulate GABA-A-r expression during pregnancy and restore its previous state after parturition appears to trigger PPD. The GABAergic system is a promising pharmacotherapy target. From preclinical to clinical studies for about twenty years the GABAergic system has been incriminated and targeted in this challenging mental disease. PMID: 31767256 [PubMed - as supplied by publisher]
This study will be the first multicenter RCT in Spanish PC settings using adapted MBCP and compassion practices to reduce symptoms of depression during pregnancy and the postpartum period.Trial registrationClinicalTrials.gov,NCT03247491. Registered on 31 July 2017.