Epidemiology of Transmitted Drug Resistance Mutations in a HIV-1 subtype-C high prevalence setting and impact on 1-year virological failure

Publication date: Available online 16 November 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Ana Lucia D. Moro, Maria Helena Rigatto
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research

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Condition:   Antibiotic Reaction Intervention:   Diagnostic Test: urine culture Sponsor:   Batool Mutar Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Rising antimicrobial resistance (AMR) is a recognised threat to global health. There is a perception that poor prescribing practices contribute to the problem, although data confirming this are limited. Reliable data on the quality of antimicrobial prescribing in UK hospitals are not available, with hospital drug-purchasing data most often being used ...
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Publication date: March 2020Source: Journal of Global Antimicrobial Resistance, Volume 20Author(s): Ana Lucia D. Moro, Maria Helena Rigatto
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsOur results indicate a polyclonal dissemination of mcr-1.1 in the environment surrounding the first MCR-producing E. coli strain reported in Ecuador. Our findings support the idea of lateral dissemination of mcr-1.1 gene between unrelated E. coli isolates
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionThe online server and web-interface are aimed at facilitating the health organizations and medical councils to monitor the antibiotic prescription and their consumption in real time. This will not only augment the existing policy-making regarding drug-resistance programs but also promote the collection and downstream exploratory analysis of huge amount of data to get a deeper insight into the epidemiology of tuberculosis and related diseases.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Date: Friday, 12 20, 2019; Speaker: Scott Olesen, Ph.D., Scientific Director, OpenBiome; Building 33; 1N09
Source: NIH Calendar of Events - Category: American Health Source Type: events
The World Health Organization earlier this year called antimicrobial resistance—pathogens’ ability to evade medical interventions—one of the 10 largest threats to global health. In the U.S. alone, according to a recent Centers for Disease Control and Prevention (CDC) report, 35,000 people die each year due to antibiotic-resistant infections. A new study published in the BMJ points to one major propagator of the problem: doctors are prescribing antibiotics when they shouldn’t. In fact, up to 43% of U.S. antibiotic prescriptions may be “inappropriate,” according to the research. Antibioti...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Research Source Type: news
Foods may potentially serve as vehicles for the transmission of antimicrobial-resistant variants of Staphylococcus aureus that are important in a human clinical context. Further, retail food products can be a cause of staphylococcal food poisoning. For these reasons and to account for source attribution and risk assessment, detailed information on the population structure, resistance, and virulence profiles of S. aureus originating from retail food products is necessary. In the current study, whole-genome sequences from 88 S. aureus isolates were subjected to bioinformatics analyses in relation to sequence types, antimicro...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
ConclusionThese data suggest that a combined 2-h infusion with a higher dosage of meropenem, including a loading dose, may be successful to achieve effective PK parameters.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Yuxue Cao, Mahdi Naseri, Yan He, Chun Xu, Laurence J. Walsh, Zyta M. ZioraAbstractBiofilms can be produced by multiple species or by a single strain of bacteria. The biofilm state enhances the resistance of the resident microorganisms to antimicrobial agents by producing extracellular polymeric substances. Typically, antibiotics are used to stop the growth of bacteria, but emerging resistance has limited their effectiveness. Bacteria in biofilms are less susceptible to antibiotics compared with their free-floatin...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
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