The continuous physiological changes of zebrafish (Danio rerio) based on metabolism under controlled thallium stress.

The continuous physiological changes of zebrafish (Danio rerio) based on metabolism under controlled thallium stress.
Chemosphere. 2020 Feb;240:124974
Authors: Li B, Zhang J, Ma J, Qiao L, Ren B, Chen M, Ren Z
Abstract
In this research, the continuous physiological changes of zebrafish (Danio rerio) in 0.1 μg/L thallium (Tl) in 15 days were investigated. The results showed that Tl(I) stress had a significant positive linear correlation with zebrafish ammonia nitrogen excretion (ANE) (p < 0.001), and the mean value of ANE in Tl(I) treatment (435 ± 227 mg/kg/h) was approximately 2 times higher than in the control group (239 ± 168 mg/kg/h), which suggested that ANE was suitable for Tl(I) stress assessment. A substantial difference based on oxygen consumption rate (OCR) between the control group (587 ± 112 mg/kg/h) and Tl(I) treatment (260 ± 88 mg/kg/h) with a high significance p < 0.001 could be observed, and the results indicated that Tl(I) played a negative role in OCR of zebrafish. The characteristics of both ANE and OCR changes under slight Tl(I) stress could be reflected by the ammonia quotient (AQ). It was noteworthy that AQ increased rapidly in first 6 h from 0.66 to 4.50, which was 3 times higher than 1.2, indicating rapid increase in both anaerobic energy utilization and protein metabolism in 0.1 μg/L Tl(I) exposure. It is concluded that the physiological changes of zebrafish ba...

Source: Chemosphere - November 17, 2019 Category: Chemistry Authors: Li B, Zhang J, Ma J, Qiao L, Ren B, Chen M, Ren Z Tags: Chemosphere Source Type: research