Comparison between the Neurological Disorders Depression Inventory for Epilepsy and the Patient Health Questionnaire-9 in patients with epilepsy according to antiepileptic drug load
Publication date: Available online 15 November 2019Source: SeizureAuthor(s): Hyo Jae Kim, Ji-Ye Jeon, Hyun-Woo Kim, Sang-Ahm LeeAbstractPurposeWe compared the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) with the Patient Health Questionnaire-9 (PHQ-9) according to different antiepileptic drug (AED) loads in people with epilepsy (PWE).MethodsDepression and suicidality were assessed with the Mini International Neuropsychiatric Interview (MINI), the NDDI-E, and the PHQ-9. A receiver operating characteristic (ROC) curve analysis was used. Sensitivity and specificity of the NDDI-E and PHQ-9 were compared between an AED load
(Aarhus University) Three of the most common forms of anti-epileptic drugs in Denmark is associated with increase in patients' risk of suicide. However, the risk is low and should be seen in conjunction with the many beneficial effects of the medicines. This is the conclusion of a new study carried out by researchers from Aarhus University and Aarhus University Hospital.
CONCLUSION: MNSS are the most burdensome disease grouping and should be prioritized for funding in Canada, Mexico, and the United States. PMID: 31747307 [PubMed - as supplied by publisher]
Objective: To determine the differences in the incidences and risks of suicide attempt (SA) and suicidal drug overdose (SDO) between patients with epilepsy with and without comorbid depression by using data from Taiwan's National Health Insurance Re...
Conclusion: Risks of SA and SDO in patients with epilepsy are proportionally increased when depression is coexisted. Our findings provide crucial information for clinicians and the government for suicide prevention and to question whether prescribing a large number of medications to patients with epilepsy and depression is safe.
Depression is common in patients with epilepsy (PWE): the prevalence of depression in PWE is about five times higher than in the general population [1,2]. The pathophysiological and psychosocial features of epilepsy put individuals at greater risk of depression, and conversely, depression has an adverse effect on epilepsy . Depression is significantly associated with drug-resistant epilepsy and poor quality of life [4,5]. Together with depression, suicide is also a serious problem in PWE. The suicide rate in PWE is about three times higher than in the general population, and is higher when accompanied by depression .
ConclusionThe Chinese version of the SSI-W proved to be a reliable and effective assessment tool for screening suicidal ideation in Chinese adult PWE.
CONCLUSION: The Chinese version of the SSI-W proved to be a reliable and effective assessment tool for screening suicidal ideation in Chinese adult PWE. PMID: 31698259 [PubMed - as supplied by publisher]
Conclusions: In>8 years of observation, most participants experienced a robust and sustained antidepressant response to SCC DBS. News in Context: Ethical issues raised around deep brain stimulation (DBS) research Closing the Circuit: Helen Mayberg’s research could revolutionize depression treatment Expo Day: Neuroenginnering, BPI, Arrowsmith Program &ARPF from SharpBrains
ConclusionsThe most common hospitalized reasons for epilepsy patients were CVD, PD and dementia, which all were common diseases in the elderly. Consequently, the hospitalization days of these patients were longer and their financial burden was heavier. Epilepsy patients with comorbid depression should be closely monitored to prevent suicide from the onset of epilepsy.
The goals of this session are to understand the risk factors and interdisciplinary diagnostic strategies for depression, anxiety, and suicide in children with epilepsy (CWE) and to discuss effective treatments for mood disorders in CWE.