NPY1RTargeted Peptide-Mediated Delivery of a Dual PPARα/γ Agonist to Adipocytes Enhances Adipogenesis and Prevents Diabetes Progression

ConclusionsThe use of the tesaglitazar-[F7, P34]-NPY conjugate is a promising strategy to make use of the beneficial PPARα/γ effects in adipocytes while potentially omitting adverse-effects in other tissues.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research