Structurally Related Edaravone Analogues: Synthesis, Antiradical, Antioxidant, and Copper-Chelating Properties.

CONCLUSION: Overall, this study reveals a subset of edaravone analogues with interesting properties. Further investigation of these compounds is foreseen in relevant models of oxidative stress-associated diseases in order to assess their therapeutic potential in such conditions. PMID: 31724516 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31724516?dopt=Abstract

Source: CNS and Neurological Disorders Drug Targets - November 12, 2019 Category: Drugs & Pharmacology Authors: LeBlanc A, Cuperlovic-Culf M, Morin PJ, Touaibia M Tags: CNS Neurol Disord Drug Targets Source Type: research