American College of Allergy, Asthma & amp; Immunology, Nov. 7-11
The 2019 Annual Meeting of the American College of Allergy, Asthma&Immunology The annual meeting of the American College of Allergy, Asthma&Immunology was held from Nov. 7 to 11 in Houston and attracted approximately 3,500 participants...
Funding Opportunity PAR-20-072 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Program Project (P01) applications. The proposed programs may address scientific areas relevant to the NIAID mission including the biology, pathogenesis, and host response to microbes, including HIV; the mechanisms of normal immune function system development and function; and immune dysfunction resulting in autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics t...
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jörg Kleine-Tebbe, Claudia Mailänder
Authors: Ring B, Burbank AJ, Mills K, Ivins S, Dieffenderfer J, Hernandez ML Abstract Objectives: Objective measurements of asthma impairment could aid teens in recognition of changes in asthma status over time. Ready access to a conventional spirometer is not realistic outside of the clinical setting. In this proof-of-concept study, we compared the performance of the VitalFlo mobile spirometer to the nSpire KoKo® sx1000 spirometer for accuracy in measuring Forced Expiratory Volume in one second (FEV1) and Forced Vital Capacity (FVC) in adolescents with asthma.Methods: Two hundred forty pulmonary function measu...
In U.S. adolescents, use of an electronic vapor product was associated with lifetime asthma, and this association was stronger when an electronic vapor product was used together with marijuana, particularly in combination with cigarette smoking.
Eosinophilic esophagitis (EoE), is an allergic disease of the esophagus that affects both children and adults and is defined by clinical, endoscopic, and histologic characteristics. Diagnostic criteria include eosinophilic infiltration of the esophagus with ≥ 15 eosinophils/high-powered field (eos/hpf), in the setting of esophageal dysfunction1. EoE is considered to be active based on histopathology - if the peak eosinophil count is ≥15 eos/hpf, the disease is considered active. EoE is in remission if the eosinophil count decreases to
The optimal approaches for monitoring sleep disturbances in adults with atopic dermatitis (AD) is not established. Multiple patient-reported outcome measures for AD and itch have sleep-related items. These items have not been validated previously.
The objectives of this review are to provide an update on the existing studies of biologics in CRSwNP and to identify potential future areas for further research.
Conclusions: Variation in the NAT1 gene modifies asthma risk in children exposed to secondhand-smoke. To our knowledge, this is the first report of a gene-environment interaction between NAT1 variants, smoke exposure, cotinine levels, and pediatric asthma. NAT1 genotype may have clinical utility as a biomarker of increased asthma risk in children exposed to smoke. PMID: 31809667 [PubMed - as supplied by publisher]