Lubricin expression in the lumbar endplate and its association with Modic changes

ConclusionLubricin is present in the lumbar endplate where it may have an anti-inflammatory role. P. acnes infection inhibits lubricin expression by cartilage endplate cells and this may facilitate the progression of MCs and endplate degeneration.The translational potential of this articleLubricin may have an anti-inflammatory role. P. acnes infection inhibits lubricin expression by cartilage endplate cells and this may facilitate the progression of MCs and endplate degeneration.

Source: Journal of Orthopaedic Translation - November 16, 2019 Category: Orthopaedics Source Type: research