Altered seric levels of albumin, sodium and parathyroid hormone may predict early mortality following hip fracture surgery in elderly

AbstractPurposeTo analyse a wide set of routine laboratory parameters at admission to predict mortality within 30 post-operative days in elderly patients with hip fracture, as well as calculate the critical values of those biomarkers.MethodData of 994 patients older than 65  years with hip fracture were analysed of which 89 (8.2%) died within 30 post-operative days. Variables described in the literature with potential influence on early mortality were collected, including demographics, fracture type, American Society of Anesthesiologists score, Charlson’s comorbidit y index and pre-operative Hodkinson’s mental test and the Katz index for activities of daily living. In addition, an exhaustive collection of biomarkers from routine blood testing at admission was performed. Critical levels of biomarkers were calculated by the method of area under ROC curve.ResultsAt admission, early mortality group had significantly higher Charlson ’s index (p = 0.001) and lower the Katz index (p = 0.001). The surgical delay also was significantly longer in that group (p = 0.001). In univariate analyses, serum concentration at admission of total protein (p = 0.004), albumin (p = 0.001), sodium (p = 0.001), and parathyroid hormone (PTH) (p = 0.001) were significantly different between both groups. In multivariate analysis, serum albumin
Source: International Orthopaedics - Category: Orthopaedics Source Type: research

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Publication date: Available online 9 December 2019Source: NeuroImageAuthor(s): Erik D. Fagerholm, Rosalyn J. Moran, Inês R. Violante, Robert Leech, Karl J. FristonAbstractModels of coupled phase oscillators are used to describe a wide variety of phenomena in neuroimaging. These models typically rest on the premise that oscillator dynamics do not evolve beyond their respective limit cycles, and hence that interactions can be described purely in terms of phase differences. Whilst mathematically convenient, the restrictive nature of phase-only models can limit their explanatory power. We therefore propose a generalisati...
Source: NeuroImage - Category: Neuroscience Source Type: research
This report describes current practice as well as complications noted following disbudding of goat kids in the Netherlands. Complications include failure to recover from anaesthesia as well as neurological symptoms and subsequent death up to two weeks after the procedure. Considerations for optimal disbudding management, including practical, legislative, technical, and anaesthesiologic concerns are briefly discussed. Data on both the safety and efficacy of local anaesthetic injections for disbudding in goat kids are scarce. Therefore, more field studies focusing on feasibility and efficacy of local anaesthetic approaches w...
Source: Small Ruminant Research - Category: Zoology Source Type: research
The patient said she was "traumatised" after feeling pain during surgery at Yeovil Hospital last year.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
ConclusionBreast pilonidal sinus is an extremely rare variant of the condition. It should be suspected on clinical examination. Surgical excision is the definitive treatment strategy.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Source: BMJ Education - Category: General Medicine Source Type: research
Massage therapy, chiropractic adjustments, herbs and supplements are most commonly recommended
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Internal Medicine, Allergy, Neurology, Nursing, Oncology, Orthopedics, Pharmacy, Psychiatry, Rheumatology, Anesthesiology & amp; Pain, Journal, Source Type: news
Conditions:   Aspiration; Gastric Contents, Anesthesia;   Intubation Complication Interventions:   Other: Application of cricoid pressure;   Other: Application of Left lateral paratracheal pressure Sponsor:   Boston Children’s Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 29 October 2019Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Anthony M.-H. Ho, Glenio B. Mizubuti
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Abstract BACKGROUND: Mechanical ventilation (MV) is identified as an independent contributor to diaphragmatic atrophy and contractile dysfunction. Appropriate sedation is also essential during MV, and anesthetics may have direct adverse effects on the diaphragm. However, there is a lack of research into the effects of different anesthetics on diaphragm function during MV. OBJECTIVES: In the present study, we aim to examine the effect of midazolam, dexmedetomidine, and propofol on diaphragm function during MV. DESIGN: Animal study. SETTING: University research laboratory. SUBJECTS: Male Wistar r...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
This page contains meeting materials for the Anesthetic and Analgesic Drug Products Advisory Committee meetings for 2020, including the meeting announcement, briefing materials, committee roster, webcast information, agenda, meeting roster, presentation slides, summary minutes, and transcript
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
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