A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers

Publication date: Available online 16 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Fabianne Carlesse, Liane Esteves Daudt, Adriana Seber, Álvaro Pimenta Dutra, Analy Salles de Azevedo Melo, Belinda Simões, Carla Macedo, Carmem Bonfimi, Eliana Benites, Lauro Gregianin, Marjorie Vieira Batista, Marcelo Abramczyk, Vivian Tostes, Henrique Lederman, Maria Lúcia de Martino Lee, Sandra Logetto, Cláudio Galvão, Arnaldo Lopes ColomboAbstractIn the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases.
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research

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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: J Cell Mol Med - Category: Molecular Biology Authors: Tags: J Cell Mol Med Source Type: research
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Source: Cancer Cell - Category: Cancer & Oncology Source Type: research
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Source: Nature AOP - Category: Research Authors: Source Type: research
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Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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