Buspirone for the Treatment of Generalized Anxiety Disorder in Williams Syndrome: A Case Series.

Buspirone for the Treatment of Generalized Anxiety Disorder in Williams Syndrome: A Case Series. J Autism Dev Disord. 2019 Nov 14;: Authors: Thom RP, Keary CJ, Waxler JL, Pober BR, McDougle CJ Abstract Co-morbid anxiety disorders, including generalized anxiety disorder (GAD), are highly prevalent among individuals with Williams syndrome (WS). However, reports of the pharmacologic treatment of only a limited number of previous anxiety disorders in WS have appeared in the literature. Here, we review the case histories of three adolescents/young adults with WS and the treatment course of co-morbid GAD with buspirone. Treatment with buspirone was well-tolerated and resulted in sustained response in all three cases. Common medical disorders in WS are highlighted with regards to safe and appropriate pharmacologic treatment of GAD. Buspirone's generally benign side effect profile is a major benefit of its use for treating GAD in individuals with WS. PMID: 31724120 [PubMed - as supplied by publisher]
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research