prevalence of functional dyspepsia symptoms in patients with asthma.

[PREVALENCE OF FUNCTIONAL DYSPEPSIA SYMPTOMS IN PATIENTS WITH ASTHMA]. Arerugi. 2019;68(9):1132-1140 Authors: Tomyo F, Sugimoto N, Toyota H, Ito A, Ujino M, Sakasegawa H, Kobayashi K, Koizumi Y, Miyoshi S, Kuramochi M, Yamaguchi M, Yamamoto T, Nagase H Abstract BACKGROUND: Gastroesophageal reflux disease (GERD) is a common comorbidity among patients with asthma. In addition, functional dyspepsia (FD) is characterized by upper abdominal symptoms without organic disease manifestations. However, the prevalence of FD among patients with asthma remains uninvestigated; therefore, herein, we investigated the prevalence of dyspepsia symptoms in these patients. METHODS: We recruited 156 patients with asthma from the outpatient clinic of Teikyo University Hospital and investigated the prevalence of dyspepsia symptoms using the modified Frequency Scale for the Symptoms of GERD. Further, the relationship between dyspepsia symptoms and clinical background of asthma was also investigated. RESULTS: Certain digestive organ symptoms were exhibited by 83% of patients with asthma, dyspepsia symptoms by 44%, and reflux symptoms by 26%. The dyspepsia-dominant group showed significantly higher female ratio and numerically lower %FEV1 than the asymptomatic group. In the group with dyspepsia score>5 points, the ratio of patients undergoing step 4 asthma treatment and the ratio of those using long-acting muscarinic receptor antagonist were higher than those in the g...
Source: Arerugi - Category: Allergy & Immunology Authors: Tags: Arerugi Source Type: research

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Authors: Zhao Z, Chang MY, Frerichs I, Zhang JH, Chang HT, Gow CH, Möller K Abstract BACKGROUND: Since bronchial abnormalities often exhibit spatial non-uniformity which may be not correctly assessed by conventional global lung function measures, regional information may help to characterize the disease progress. We hypothesized that regional air trapping during mechanical ventilation could be characterized by regional end-expiratory flow (EEF) derived from electrical impedance tomography (EIT). METHODS: Twenty-five patients suffering from chronic obstructive pulmonary disease (COPD grade 3 or 4) or severe...
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
We examined our primary care birth cohort of 158,510 pediatric patients, of whom 214 patients met 2017 FPIES diagnostic criteria. We measured the influence of FPIES on developing subsequent atopic disease.ResultsPediatric FPIES incidence was between 0.17% and 0.42% depending on birth year. As in prior reports, most patients had an acute presentation (78%), and milk, soy, oat, rice, potato, and egg were common triggers. The mean age of diagnosis was 6.8 months. Atopic comorbidity was higher in patients with FPIES compared with healthy children (AD, 20.6% vs 11.7%; IgE-FA, 23.8% vs 4.0%; asthma, 26.6% vs 18.4%; AR, 28.0% vs 16.7%; P
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
We present the case of a 4-year-old child who was admitted owing to the complaint of recurrent pancreatitis and had not previously been diagnosed with having metabolic disease. During inpatient treatment for acute pancreatitis, convulsions occurred with concomitant hyperammonemia, metabolic acidosis, coagulopathy, and shock 1 week after the administration of total parenteral nutrition. He was diagnosed to have PA after a metabolic work-up and confirmed to have novel mutation by molecular genetic analysis. Because children with PA may have acute pancreatitis, although rare, vomiting and abdominal pain should raise a suspici...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Nocardiosis is an uncommon infection caused by ubiquitous environmental aerobic gram-positive filamentous bacteria, present in soil and water. Skin and lungs are usually the main targets of localized infections. Rarely, disseminated forms can occur in immunocompromised individuals. A 63-year-old man with a history of late-onset asthma and nasal and sinus polyposis treated with oral low-dose corticosteroid regimen presented with fever, headache, myalgia, skin erythematous plaques, and pustules. Brain MRI revealed multiple abscesses and pachymeningitis. 18F-FDG PET/CT was performed to assess the extent of the infection. Cuta...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Publication date: Available online 7 December 2019Source: Nano EnergyAuthor(s): Gang Wang, Li Ping Liao, Ahmed Mourtada Elseman, Yan Qing Yao, Chun Yan Lin, Wei Hu, De Bei Liu, Cun Yun Xu, Guang Dong Zhou, Ping Li, Li Jia Chen, Juan Juan Han, Xiu De Yang, Rong Wu, Xi Rao, Qun Liang SongAbstractHot carriers and their extraction have been demonstrated in organic-inorganic perovskites under transient condition. Unfortunately, there was no real device to harvest hot carriers under steady-state illumination yet due to the indistinguishable hot and cooled carriers in conventional sandwiched structure. Here we report a new design...
Source: Nano Energy - Category: Nanotechnology Source Type: research
Conclusions: Successful treatment of GER-associated cough may be associated with the attenuation of neurogenic and neutrophilic inflammation. PMID: 31303089 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Acid-suppressive medications, such as H2-receptor antagonists (H2RA) and proton pump inhibitors (PPI), are the main treatment options for dyspepsia and gastroesophageal reflux disease. These are common problems in pregnancy.1 Recently, concerns have been raised that prenatal exposure to these medications may increase the risk of allergic disease in the offspring.1 Dehlink et  al1 were the first to report these associations, proposing that use of acid-suppressive medications in pregnancy may increase the risk of allergic disease in the offspring through interference with maternal digestion of labile antigens, ther...
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Letter to the Editor Source Type: research
Conclusion Chronic rhinosinusitis was diagnosed in more than 40% of children with dyspepsia. The odds of CRS being present in children diagnosed to have GERD increases significantly as demonstrated in this study.
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - Category: ENT & OMF Source Type: research
We have previously suggested that oesophageal dysfunction may underlie a number of otherwise unexplained respiratory symptoms particularly chronic cough. However on conventional testing of oesophageal function using pH and impedance techniques few patients are abnormal. We have compared patients with unexplained respiratory symptoms with a control group with dyspepsia and heartburn using High Resolution Oesophageal Manometry.121 patients were studied, 61 with respiratory complaints and 60 with primarily gastrointestinal symptoms. Respiratory patients consisted of 38 females, combined mean age of 56, range (18 – 81) a...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 5.2 Monitoring Airway Disease Source Type: research
Conclusion: Daytime phlegm and losing the sense of smell suggest that eosinophilic airway inflammation persists, despite anti-inflammatory therapy, in patients with asthma. Although rhinitis and GERD made the subjective symptoms of asthma worse, they did not seem to enhance eosinophilic airway inflammation. Keywords: asthma symptoms, FeNO, rhinosinusitis, GERD, dyspepsia 
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
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