Teenage boy with lipoma arborescens of the knee and elbow and presumed juvenile idiopathic arthritis

Abstract16 ‐year‐old boy with severe obesity presented to the pediatric rheumatology clinic with a 1.5‐year history of right knee swelling. Laboratory findings were unremarkable other than mildly elevated inflammatory markers. Lyme screen was negative. A previous knee MRI reported a large joint effusion with synovitis and few punctate foci of low signal intensity throughout the synovium, concerning for pigmented villondodular synovitis.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Clinical Image Source Type: research

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Publication date: Available online 10 December 2019Source: Small Ruminant ResearchAuthor(s): J. Reintke, K. Brügemann, H. Wagner, P. Engel, A. Wehrend, S. KönigAbstractThere is an increasing economic pressure in sheep production. Hence, it is imperative to use all available tools contributing to improvements in lamb survival. In this regard, there is a lack of studies addressing the impact of maternal body condition traits on lamb performances during lactation. Specifically, the focus of the present study was to analyse associations between ewe traits reflecting maternal energy metabolism and lamb body weight (LB...
Source: Small Ruminant Research - Category: Zoology Source Type: research
Conclusions: A significant increase (P = .02) in Lyme arthritis cases was observed at Oishei Children's Hospital of Buffalo. Lyme arthritis may clinically present similarly to other forms of arthritis, such as oligoarticular juvenile idiopathic arthritis, so health care providers should be aware of distinguishing clinical features, which include rapid onset of swelling and patient age. Because the geographic area of endemic Lyme disease is expanding, all health care providers need to be aware of Lyme arthritis as a possible diagnosis. PMID: 31819695 [PubMed]
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
Applied Physiology, Nutrition, and Metabolism, e-First Articles. We are currently facing an “obesity epidemic” worldwide. Promoting inefficient metabolism in muscle represents a potential treatment for obesity and its complications. Sarco(endo)plasmic reticulum (SR) Ca2+-ATPase (SERCA) pumps in muscle are responsible for maintaining low cytosolic Ca2+ concentration through the ATP-depe ndent pumping of Ca2+ from the cytosol into the SR lumen. SERCA activity has the potential to be a critical regulator of body mass and adiposity given that it is estimated to contribute upwards of 20% of daily energy expenditure....
Source: Applied Physiology, Nutrition, and Metabolism - Category: Physiology Authors: Source Type: research
This study describes the nutritional status of Qom preschoolers in general, and by neighborhood area and family's socioeconomic characteristics in a peri-urban village of Formosa, Argentina. Across-sectional study was carried out between January and December 2016, with 160 Qom children between 2 and 5 years of age. Interviews and anthropometric measures were conducted at the children's homes. Nutritional status was determined by body mass index. The prevalence of excess weight (overweight + obesity) and of stunting were associated with neighborhood area and socioeconomic level. The overall prevalence of stunting was 15.6% ...
Source: Ecology of Food and Nutrition - Category: Nutrition Tags: Ecol Food Nutr Source Type: research
Authors: Singh AK, Singh R Abstract BACKGROUND: Lorcaserin is a novel, selective 5-hydroxytryptamine 2C serotonin receptor agonist, approved for the treatment of obesity. Several phase 3 randomized controlled trials (RCTs) trials have shown a significant reduction in body weight with lorcaserin. RESEARCH DESIGN AND METHODS: We systematically searched the database of PubMed, Embase, The Cochrane Library and ClinicalTrials.gov up to July 31, 2019 and retrieved all the studies conducted with lorcaserin for ≥ 1-year that have explicitly reported the efficacy and safety outcomes versus placebo. Subsequently, we s...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Authors: Umapathy S, Thulasi R, Gupta N, Sivanadhan S Abstract The aim and objectives of this study were as follows: (i) to perform automated segmentation of knee thermal image using the regional isotherm-based segmentation (RIBS) algorithm and segmentation of ultrasound image using the image J software; (ii) to implement the RIBS algorithm using computer-aided diagnostic (CAD) tools for classification of rheumatoid arthritis (RA) patients and normal subjects based on feature extraction values; and (iii) to correlate the extracted thermal imaging features and colour Doppler ultrasound (CDUS) features in the knee re...
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
Authors: Dayan D, Kuriansky J, Abu-Abeid S Abstract BACKGROUND: The Roux-en-Y gastric bypass (RYGB) surgery helps patients achieve excellent excess weight loss, with subsequent improvement or resolution of co-morbidities. However, up to 20% of all RYGB patients, and 40% of the super morbidly obese, experience significant weight regain. The etiology of weight regain is multifactorial; hence, multidisciplinary management is mandatory. Revision options for failed conservative and medical management include resizing the restrictive component of the bypass or intensifying malabsorption. While improvement of restriction ...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
Conditions:   Intermittent Fasting;   Obesity, Morbid;   Comorbidities and Coexisting Conditions;   Weight Loss;   Fluid Retention Intervention:   Behavioral: Intermittent fasting Sponsor:   Tel-Aviv Sourasky Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Obesity;   Weight Loss Interventions:   Other: Multidisciplinary weight loss program;   Other: Standard Care;   Drug: Metformin Hcl 850Mg Tab Sponsor:   American University of Beirut Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Airway Management;   Obesity Interventions:   Device: Air-Q intubating laryngeal airway;   Device: Ambu-Aura intubating laryngeal mask Sponsor:   Cairo University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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