The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes
Condition: Type 2 Diabetes Interventions: Dietary Supplement: crocin; Dietary Supplement: placebo Sponsors: National Nutrition and Food Technology Institute; Vahideh Behrouz; Ali Dastkhosh Completed
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Authors: Curran JA, Haynes A, Davis EA PMID: 31808549 [PubMed - as supplied by publisher]
ConclusionsOur investigations did not show enough evidence for the presence of an association betweenKCNQ1 gene rs2237892 polymorphism and risk of T2DM among a group of Iranian patients.
Publication date: Available online 6 December 2019Source: Canadian Journal of DiabetesAuthor(s): Tomoyuki Kawada
Publication date: Available online 7 December 2019Source: Saudi Pharmaceutical JournalAuthor(s): Sirajudeen Shaik Alavudeen, Moteb Khobrani, C.K. Dhanapal, Javid Iqbal Mir, Sultan Mohammed Alshahrani, Noohu Abdullah Khan, Abdulaziz Alhossan
This study investigated the effects of glibenclamide on transplant-induced arteriosclerosis as well as the underlying molecular events.MethodsMale C57Bl/6 (H-2b) and BALB/c (H-2d) mice were used for aorta transplantation. We used hematoxylin and eosin (HE) and Elastic Van Gieson (EVG) staining for histological assessment, and qRT-PCR and ELISA to measure mRNA and protein levels. Mouse peritoneal macrophages were isolated for lipopolysaccharide (LPS) stimulation and glibenclamide treatment followed by ELISA, Western blot, and Transwell assays.ResultsGlibenclamide inhibited transplant-induced arteriosclerosis in vivo. Morpho...
An estimated 30 million Americans are living with diabetes. That ’s over 9% of the nation, but there are warning signs. One is the condition known as prediabetes, where blood sugar levels are higher than normal, but below the range for type 2 diabetes. Data from 2005 to 2016 shows that nearly one in five American children ages 12 to 18 were prediabetic. CBS New s Medical Contributor Dr. David Agus joins "CBS This Morning Saturday" to discuss this condition, as well as a new diet trend.
We examined the relationships among dietary patterns, dietary biomarkers, and metabolic indicators in type 2 diabetes (n = 871). Design: Diabetic patients (n = 871) who provided complete clinical and dietary data in both 2008 and 2009 were selected from a cohort participating in a diabetic control study in Taiwan. Dietary data were obtained using a short, semiquantitative food frequency questionnaires, and dietary pattern identified by factor analysis. Multiple linear regressions were used to analyze the association between dietary biomarkers (ferritin, folate, and erythrocyte n-3 polyunsaturated fatty acids [n-3 PUFA...
Conclusions: Our estimated rates of prevalence of GP in T1DM and T2DM indicate that GP is not a common clinical complication in these populations. Majority of EMRs that indicated a diagnosis of GP did not include any documentation of definitive diagnostic testing (EGD and/or GES).
TYPE 2 diabetes affects a person ’s blood sugar levels, and left untreated, serious complications can occur. When it comes to keeping blood sugar levels in check, eating a certain meal for breakfast could help.