Functional signs in patients consulting for presumed Lyme borreliosis.

Functional signs in patients consulting for presumed Lyme borreliosis. Med Mal Infect. 2019 Nov 10;: Authors: Voitey M, Bouiller K, Chirouze C, Fournier D, Bozon F, Klopfenstein T Abstract INTRODUCTION: Little is known about the functional symptoms associated with Lyme borreliosis (LB) in Europe. We aimed to assess functional symptoms associated with presumed LB and to compare patients with and without confirmed LB. MATERIALS AND METHODS: We performed a retrospective monocenter study. Patients consulting for presumed LB were included. RESULTS: Between November 2015 and June 2018, 355patients were included (mean age: 51years, 52% of women) of which 48had LB: erythema migrans (42%), early disseminated LB (50%; 35% of neuroborreliosis cases), and late disseminated LB (8%). The most frequently reported functional symptoms were neuropathic pain (23%), arthralgia (23%), and asthenia (17%). Other functional symptoms were rare (≤10%). Three hundred and seven (86%) patients did not have LB. Patients with confirmed LB reported fewer functional symptoms than patients without LB (1.8 (±1.7) vs. 3.6 (±2.5), P
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

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We report a case of suspected Lyme neuroborreliosis (LNB) where the patient's sole symptom was chronic, intermittent episodes of unilateral ear pain. This case was unusual because this patient did not show any other neurological or extraneurological symptoms of Lyme disease. LNB is a manifestation of infection by Borrelia burgdorferi spirochetes that can manifest in a number of different clinical presentations depending on the nervous system dissemination of the bacteria. Most commonly, these neurological findings present as peripheral nerve radiculopathies, but rarer involvement of the central nervous system (CNS) can...
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
This study is registered with the Netherlands Trial Registry, number NTR5263.FindingsWe screened patients for enrolment between Dec 3, 2015, and May 31, 2018. Patients completed baseline visits and started treatment between Dec 14, 2015, and July 2, 2018, and the last study visit of the last patient was Oct 4, 2018. Of 149 patients assessed for eligibility, 57 (38%) patients were excluded (predominantly because they did not meet one or several inclusion criteria, most often because of an absence of synovial inflammation or of flare-ups after NSAID washout) and 92 (62%) patients were eligible for inclusion. We randomly assi...
Source: The Lancet - Category: General Medicine Source Type: research
DR MARTIN SCURR: Pat Toovey from Norfolk found a tick on his wife's back two years ago and she is constantly in pain and struggles to get out of bed. He fears she has Lyme disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In 1975, researchers from Yale investigated an epidemic of 51 patients with arthritis who lived near the woodsy town of Lyme, Connecticut. The most common symptom was recurrent attacks of knee swelling. A few had pain in other joints, such as the wrist or ankle. Many had fever, fatigue, and headache. Some remembered a round skin rash before the onset of knee swelling. We now know that Lyme disease is an infection acquired from tick bites, caused by a spiral bacterium named Borrelia burgdorferi. After a tick bite, Borrelia bacteria wriggle through the skin away from the bite site. This leads to a circular red rash, known as...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Infectious diseases Source Type: blogs
Just over 20 years ago, a Lyme disease vaccine called LYMErix was approved for sale in the United States. Researchers designed the vaccine to prevent the transmission of the tick-borne pathogen Borellia burgdorferi, which spurs a bacterial infection that can cause fever, headaches, and joint pain if left untreated. The...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Inner Workings, Front Matter Source Type: research
Dr. Derek Monette: Today's case is that of a 46-year-old male with recent diagnoses of Lyme disease and babesiosis who presented to our emergency department (ED) with abdominal pain, nausea, and diarrhea. The patient was previously healthy and had been well until approximately 2  weeks before the day of ED presentation, when he developed headache, fatigue, and myalgias. He also noticed that his right calf “looks sunburned,” and was warm to the touch. He was evaluated by his primary care physician (PCP) after 1 week of symptoms.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Case Presentations of the Harvard Affiliated Emergency Medicine Residencies Source Type: research
Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
After my tick bite I realised that the climate crisis was a more likely culprit than any conspiracy theory about weaponisationThe first indication I ’d picked up a tick-borne disease three years ago was the excruciating arthritic pain in my feet as I hobbled to a dinner party at a neighbour’s house in Jerusalem.Later that night I experienced flu-like symptoms, including a raging fever that, even with antibiotics, would last for more than a week.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Insects Weapons technology Wildlife Animals Science World news Environment US news Source Type: news
PMID: 31259503 [PubMed - in process]
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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