Viruses, Vol. 11, Pages 1069: In Vivo Characterization of Tick-Borne Encephalitis Virus in Bank Voles (Myodes glareolus)

Viruses, Vol. 11, Pages 1069: In Vivo Characterization of Tick-Borne Encephalitis Virus in Bank Voles (Myodes glareolus) Viruses doi: 10.3390/v11111069 Authors: Michelitsch Tews Klaus Bestehorn-Willmann Dobler Beer Wernike Tick-borne encephalitis is the most important tick-transmitted zoonotic virus infection in Eurasia, causing severe neurological symptoms in humans. The causative agent, the tick-borne encephalitis virus (TBEV), circulates between ticks and a variety of mammalian hosts. To study the interaction between TBEV and one of its suspected reservoir hosts, bank voles of the Western evolutionary lineage were inoculated subcutaneously with either one of eight TBEV strains or the related attenuated Langat virus, and were euthanized after 28 days. In addition, a subset of four strains was characterized in bank voles of the Carpathian linage. Six bank voles were inoculated per strain, and were housed together in groups of three with one uninfected in-contact animal each. Generally, most bank voles did not show any clinical signs over the course of infection. However, one infected bank vole died and three had to be euthanized prematurely, all of which had been inoculated with the identical TBEV strain (Battaune 17-H9, isolated in 2017 in Germany from a bank vole). All inoculated animals seroconverted, while none of the in-contact animals did. Viral RNA was detected via real-time RT-PCR in the whole blood samples of 31 out of 74 inoculated and su...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research

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Tick-borne encephalitis (TBE) is a zoonotic neurological disease caused by tick-borne encephalitis virus (TBEV), a flavivirus endemic in parts of Europe and Asia. Seroconversion without signs of clinical disea...
Source: Acta Veterinaria Scandinavica - Category: Veterinary Research Authors: Tags: Case report Source Type: research
Japanese encephalitis (JE), a human viral disease highly prevalent in Asian countries, is transmitted via a zoonotic cycle between vector mosquitoes, such as Culex tritaeniorhynchus, and pigs or water birds as amplifiers (Pearce et al., 2018). The causative pathogen, JE virus (JEV), is a flavivirus of the family Flaviviridae, which includes dengue, Zika, yellow fever, and tick-borne encephalitis viruses (Lazear and Diamond, 2016). JEV has a positive-sense single-stranded RNA genome that may cause asymptomatic infection in some patients and severe neurological manifestations resulting in death in others (Solomon, 2003).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
In this study, we took advantage of the recently compiled spatial dataset of distribution and diversity of ticks in China, analyzed the environmental determinants of ten frequently reported tick species and mapped the spatial distribution of these species over the country using the MaxEnt model. We found that presence of urban fabric, cropland, and forest in a place are key determents of tick occurrence, suggesting ticks were likely inhabited close to where people live. Besides, precipitation in the driest month was found to have a relatively high contribution in mapping tick distribution. The model projected that theses t...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Tick distribution in Sweden has increased in recent years, with the prevalence of ticks predicted to spread towards the northern parts of the country, thus increasing the risk of tick-borne zoonoses in new reg...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Vector-Borne and Zoonotic Diseases, Ahead of Print.
Source: Vector-Borne and Zoonotic Diseases - Category: Infectious Diseases Authors: Source Type: research
AbstractPurpose of ReviewIn this review, we present the overview of emerging and neglected viruses associated with liver involvement.Recent FindingsHepatitis E virus (HEV) emerged in the last two decades, causing hepatitis in many parts of the world. Moreover, liver involvement was also described in some emerging arboviral infections. Many reports showed dengue-associated liver injury; however, chikungunya, West Nile, tick-borne encephalitis, and Zika virus are rarely associated with clinically manifest liver disease. In addition, some neglected highly prevalent viruses such as adenoviruses and parvovirus B19 are capable o...
Source: Current Infectious Disease Reports - Category: Infectious Diseases Source Type: research
In conclusion, these newly developed cell lines may represent useful tools to study virus-cell interactions and to identify and characterize host cell factors involved in replication of rodent associated viruses. PMID: 31513859 [PubMed - as supplied by publisher]
Source: Journal of Virological Methods - Category: Virology Authors: Tags: J Virol Methods Source Type: research
Publication date: Available online 15 August 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Jiří Černý, Buyantogtokh Buyannemekh, Tersia Needham, Gantulga Gankhuyag, Dashzeveg OyuntsetsegAbstractTicks and tick-borne pathogens (TBPs) pose a considerable threat to human and animal health in Mongolia; a large and sparsely inhabited country whose economy is largely dependent on animal production. Intensive contact between herdsmen and their livestock, together with the use of pastures without fencing, allows contact between wildlife, domestic animals and humans, thus creating ideal conditions for epizoonos...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Abstract Tick-borne encephalitis virus (TBEV) is a zoonotic agent causing severe encephalitis. The transmission cycle involves the virus, the Ixodes tick vector, and a vertebrate reservoir, such as small mammals (rodents, or shrews). Humans are accidentally involved in this transmission cycle. Tick-borne encephalitis (TBE) has been a growing public health problem in Europe and Asia over the past 30 years. The mechanisms involved in the development of TBE are very complex and likely multifactorial, involving both host and viral factors. The purpose of this review is to provide an overview of the current lite...
Source: Critical Reviews in Microbiology - Category: Microbiology Authors: Tags: Crit Rev Microbiol Source Type: research
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