Response to commentary on “Therapeutic hypothermia attenuates paraplegia and neuronal damage in the lumbar spinal cord in a rat model of asphyxial cardiac arrest” by Lee et al.,. J Therm Biol 83 (2019) 1–7."

Publication date: Available online 15 November 2019Source: Journal of Thermal BiologyAuthor(s): Jae-Chul Lee, Moo-Ho Won
Source: Journal of Thermal Biology - Category: Biology Source Type: research

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Background: Although hypothermia is known to have protective effects against ischemic injuries, the effects of hypothermia on kidney injury have not yet been elucidated. Therefore, this study aimed to identify the association between intraoperative hypothermia and postoperative acute kidney injury (AKI) in patients who underwent spine surgery under general anesthesia. Methods: In this retrospective observational study, we analyzed the medical records of adult patients who underwent elective spine surgery between January 2010 and March 2018. Patients were classified into the normothermia group (36.5 to 37.5°C), mil...
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research
AbstractWe previously reported that the inactivation (cKO) or the stabilization (cST) of β-catenin in cells expressing the astrocyte-specific glutamate aspartate transporter (GLAST) is associated with the vulnerability or resilience to exhibit anxious/depressive-like behaviors, respectively, and to changes in hippocampal proliferation. Here, we used these cKO and cST β-catenin mice to study the serotonergic system functionality associated with their behavioral/molecular phenotype. The activity of 5-HT1A receptors was assessed by (+)-8-OH-DPAT-induced hypothermia and [35S]GTP γS binding autoradiography. The ...
Source: Molecular Neurobiology - Category: Neurology Source Type: research
This study proposes a multi-center RCT in order to compare outcomes of warmer hypothermic strategies during aortic hemiarch surgery on a composite endpoint of neurologic and acute kidney injury (AKI).Methods/designThis is a prospective multi-center, single-blind two-arm RCT comparing mild (32  °C) versus moderate (26 °C) hypothermic cardiac arrest in patients (n = 282) undergoing hemiarch surgery with antegrade cerebral perfusion (ACP). The primary endpoint is a composite of neurological injury (incidence of transient ischemic attack and/or stroke) and Kidney Disease Improving Global Out...
Source: Trials - Category: Research Source Type: clinical trials
Hypothermia on the battlefield has been shown to be associated with severe injury and higher mortality. The incidence of battlefield casualties presenting to with hypothermia are described.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
A British woman has made a full recovery after suffering a six-hour cardiac arrest caused by severe hypothermia -- a condition that doctors say also saved her life.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
A 34-year-old British hiker was revived in Spain after a six-hour cardiac arrest brought on by severe hypothermia, with the low mountain temperatures that made her ill also helping to save her life in what a doctor described as an"exceptional case."Reuters Health Information
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Cardiology News Source Type: news
Audrey Mash got caught in a snowstorm while hiking in the Pyrenees. Doctors say she experienced the longest period of cardiac arrest that a patient has survived in Spain.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Hikes and Hiking Hypothermia Heart Rescues Pyrenees Mountains Barcelona (Spain) Great Britain Audrey Schoeman Source Type: news
A British woman has made a full recovery after suffering a six-hour cardiac arrest caused by severe hypothermia -- a condition that doctors say also saved her life.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
CONCLUSION: Hypothermia in the first hour of life was prevalent in preter m infants, being associated with clinical complications. The prevention of hypothermia in the first hour of life is fundamental in the reduction of diseases related to prematurity. PMID: 31800797 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
Audrey Mash got caught in a snowstorm while hiking in the Pyrenees. Doctors say she experienced the longest period of cardiac arrest that a patient has survived in Spain.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Hikes and Hiking Hypothermia Heart Rescues Pyrenees Mountains Barcelona (Spain) Great Britain Audrey Schoeman Source Type: news
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