Factors influencing decline in quality of life in smokers without airflow obstruction: The COPDGene study

Current and former smokers with normal spirometry and with Preserved Ratio Impaired Spirometry (PRISm) experience respiratory events similar to chronic obstructive pulmonary disease (COPD) exacerbations. Exacerbations significantly reduce quality of life (QoL) in COPD patients however the effect of respiratory exacerbations on QoL in these groups is unknown. We hypothesized that exacerbations and change in exacerbation status would predict QoL decline among normal spirometry and PRISm participants in COPDGene.

Source: Respiratory Medicine - November 13, 2019 Category: Respiratory Medicine Authors: Trisha M. Parekh, Smita Bhatia, Andrea Cherrington, Young-il Kim, Allison Lambert, Anand Iyer, Elizabeth A. Regan, Dawn L. DeMeo, MeiLan Han, Mark T. Dransfield Source Type: research