Impact of baseline calibration on semiquantitative assessment of myocardial perfusion reserve by adenosine stress MRI

In conclusion, baseline division reliably corrects for inhomogeneity of the surface coil sensitivity pr ofile facilitating comparisons of regional myocardial perfusion during hyperemia or at rest. However, in the assessment of MPRI, baseline division can lead to paradoxical low results (even MPRI <  1.0 in patients with unobstructed coronary arteries) potentially mimicking severely impaired perfusion reserve. Thus, in the assessment of MPRI we propose to waive baseline calibration.
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research