Effects of Lifestyle Measures and Conventional Therapy in Gout

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Source: Lippincott's Bone and Joint Newsletter - Category: Orthopaedics Tags: CME Article Source Type: news

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Discussion and conclusionsIn patients with episodes of recurrent arthritis with associated joint effusion in one or two joints, refractory to systemic treatments, to local infiltrations with corticosteroids and for patients for whom other treatments may be contraindicated, we must consider the possibility of performing an isotope radiosinoviortesis, as it is a simple, safe technique with a success rate of more than 50%.ResumenNuestro hospital es el hospital de referencia en medicina nuclear para la realización de la sinoviortesis radioisotópica para toda Castilla La-Mancha.ObjetivoDescribir la experiencia en ...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
We report FDG PET/CT images of a 63-year-old woman referred for characterization of osteolytic lesions of the cervical spine. This patient with chronic renal failure had a history of follicular thyroid carcinoma with undifferentiated cells, treated by a total thyroidectomy, completed by radioactive iodine in 2017. Because of cancer history, a FDG PET/CT was performed and showed multiple moderately hypermetabolic osteolytic lesions of the spine from C3 to T1, with joint erosion on CT. A laminectomy was performed for cervical spinal cord decompression and revealed a gouty tophus.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Authors: Jadhav PP PMID: 31808459 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
ConclusionsThe studied adolescent population showed sUA level and hyperuricemia prevalence which are even higher than those of adults in China. The epidemic of youth hyperuricemia may pose a future threat of gout attacks and other hyperuricemia-related diseases, which alarms the public, health professionals and health policy makers to prepare the future health challenges.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
Publication date: January 2020Source: Microchemical Journal, Volume 152Author(s): Nada S. Abdelwahab, Hossam M. Hassan, Asmaa M. Aboul MagdAbstractColchicine, is a natural amide containing anti-gout treatment with versatile applications. Microwave assisted hydrolytic degradation is a newly alternative method thought to be more promising than traditional procedures of heating. It is an ecofriendly method that has more reproducible results due to the control of parameters. From this point, hydrolytic degradation of colchicine was tested for the first time under acidic conditions with the aided of microwave. The drug was hydr...
Source: Microchemical Journal - Category: Chemistry Source Type: research
ConclusionThe serum uric acid lowering effect and safety of dotinurad were confirmed in hyperuricemic patients with or without gout.ClinicalTrials.gov IdentifierNCT02416167
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
Monosodium urate (MSU) crystal formation, deposition and gout flares frequently affect joints that have been damaged or are affected by osteoarthritis. These researchers examined the effects of human cartilage homogenates on MSU crystallization and MSU crystal-induced inflammation...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Crystal Arthritis Arthritis & Rheumatology Gout monosodium urate crystals osteoarthritis (OA) Source Type: research
(Natural News) A form of inflammatory arthritis, gout occurs due to high levels of uric acid in the blood. The acid, which is a byproduct from when the body breaks down purines in foods, causes needle-like crystals to form in a joint. This results in pain and discomfort, typically in the ankles, knees and toes....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Purpose of review Hyperuricemia is highly prevalent, affecting approximately 38 million individuals in the United States. However, the significance of asymptomatic hyperuricemia – hyperuricemia in the absence of gout – continues to be debated. Recent findings Asymptomatic hyperuricemia results in monosodium urate crystal deposition in tissues, which may promote chronic inflammation. Intracellularly, hyperuricemia inhibits the master regulator adenosine monophosphate (AMP)-associated protein kinase and may condition innate immune responses through durable epigenetic modifications. At the population level, a...
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: MEDICAL PHYSIOLOGY AND RHEUMATIC DISEASES: Edited by Jose U. Scher Source Type: research
Nature Reviews Rheumatology, Published online: 29 November 2019; doi:10.1038/s41584-019-0347-yLDHD mutation leads to hyperuricaemia and gout
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Source Type: research
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