Widespread Choriocarcinoma Metastases from De-differentiated Gastro-esophageal Junction Primary Adenocarcinoma: A Case Report with Literature Review

ConclusionsChoriocarcinomas can rarely originate outside of the female reproductive tract (non-gestational, primary choriocarcinomas). In the infrequent cases where a gestational origin is clinically unlikely, the differential diagnosis includes a non-gestational primary choriocarcinoma and choriocarcinomatous differentiation in another primary malignancy. Careful correlation with imaging and clinico-pathologic studies is paramount to determining their origin and guiding further clinical treatment.
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research