Nigeria: 13 States to Benefit From $250m World Bank Loan for Malaria Control

[This Day] Abuja -The federal government is about to secure a $250 million World Bank facility to fund intervention programmes to check malaria disease in 13 states of the federation, which are not currently covered by the existing government intervention programmes.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news

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Date: Tuesday, 01 07, 2020; Speaker: Daniel Neafsey, Assistant Professor, Harvard T.H. Chan School of Public Health; 5625 Fishers Lane; 5th Floor Conference Room
Source: NIH Calendar of Events - Category: American Health Source Type: events
The Theranos fiasco (see:The rise and fall of Theranos, the blood-testing startup that went from Silicon Valley darling to facing fraud charges) served to cast a pall over the micro-sample diagnostics market. Now comes news about an Israeli company with a similar strategy but this time with an instrument providing a complete blood count (CBC) and a green light from the FDA (see:Unlike Theranos, startup ’s blood test device ‘delivers on promise’ with FDA nod). Below is an excerpt from the article:Israeli startupSight Diagnostics has received US Food and Drug Administration clearance to market a blood ...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: AI Clinical Lab Testing Diagnostics Food and Drug Administration Healthcare Information Technology Healthcare Innovations Medical Research Point-of-Care Testing Source Type: blogs
[Premium Times] No fewer than 16,992 children below the age of five were treated of malaria under the EU/UNICEF Maternal, New-born and Child Health and Nutrition (MNCHN) project in Adamawa.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Contributors : Lauren M Smith ; Francis Motta ; Garima Chopra ; J K Moch ; Robert R Nerem ; Bree Cummins ; Kimberly E Roche ; Christina M Kelliher ; Adam R Leman ; John Harer ; Tomas Gedeon ; Norman C Waters ; Steven B HaaseSeries Type : Expression profiling by high throughput sequencingOrganism : Plasmodium falciparumThe blood-stage infection of the malaria parasite, Plasmodium falciparum, exhibits a 48-hour developmental cycle that culminates in the synchronous release of parasites from red blood cells, triggering 48-hour fever cycles in the host. This cycle could be driven extrinsically by host circadian processes, or b...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Plasmodium falciparum Source Type: research
Many subsistence farmers in rural southeastern Tanzania regularly relocate to distant farms in river valleys to tend to crops for several weeks or months each year. While there, they live in makeshift semi-ope...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
Malaria infection can present with a wide variety of symptoms, ranging from mild to severe. Plasmodium falciparum isolates in uncomplicated and severe malaria infections may have different parasite genetic profil...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
The long-lasting insecticidal nets (LLIN) are effective against prevention of malaria and its utilization has been proven to save lives. Despite the mass distribution of LLIN, Nigeria remains the country with ...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
Conclusion: Our findings revealed that EL significantly reduced blood uric acid levels, prevented pathological changes of kidney in PO induced hyperuricemia animal model, and improved renal urate transports. We partly clarified the mechanism was related to suppressing effect of URAT1 by quassinoid in EL. This study is the first to demonstrate that EL plays a role in hyperuricemia by promoting renal uric acid excretion.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
arimantas Čėnas With the aim to clarify the mechanism(s) of action of nitroaromatic compounds against the malaria parasite Plasmodium falciparum, we examined the single-electron reduction by P. falciparum ferredoxin:NADP+ oxidoreductase (PfFNR) of a series of nitrofurans and nitrobenzenes (n = 23), and their ability to inhibit P. falciparum glutathione reductase (PfGR). The reactivity of nitroaromatics in PfFNR-catalyzed reactions increased with their single-electron reduction midpoint potential (E17). Nitroaromatic compounds acted as non- or uncompetitive inhibitors towards PfGR with respect to NADPH and glutathione...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Natural killer (NK) cells are known to be activated during malaria infection, exhibiting both cytokine production and cytotoxic functions. However, NK cells are heterogeneous in their expression of surface activatory and inhibitory receptors which may influence their response to malaria parasites. Here, we studied the surface marker profile and activation dynamics of NK cells during a Controlled Human Malaria Infection in 12 healthy volunteers. Although there was significant inter-patient variability in timing and magnitude of NK cell activation, we found a consistent and strong increase in expression of the activatory rec...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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