Assessment of prevalence and risk factors of helicobacter pylori infection in an oilfield Community in Hebei, China

Only a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylor...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Research article Source Type: research

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Chem. Commun., 2020, Advance Article DOI: 10.1039/C9CC07915G, CommunicationGuangzong Tian, Chunjun Qin, Zhonghua Liu, Dacheng Shen, Xiaopeng Zou, Junjie Fu, Jing Hu, Peter H. Seeberger, Jian Yin Unique α-(1 → 2)- and α-(1 → 3)-linked oligoglucosides from theH. pylori serotype O2 O-antigen were synthesized with exclusive α-selectivity using remote participation effects. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Cochrane China Network working groups had an informal meeting included in the 13th China Health Technology Assessment Forum, hosted by Prof Yingyao Chen (from Fudan University) on 17th November.Eight Cochrane China Network working groups reported their work on Cochrane and some achievements in health technology assessment Cochrane. Prof Jianping Liu (Beijing University of Chinese medicine) gave the opening session, and introduced Cochrane China network and the whole session.Prof Shiyao Chen, from Zhongshan hospital affiliated to Fudan University, talked about “The clinical decision on screening helicobacter pylori fo...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
Authors: Zhang F, Chen C, Hu J, Su R, Zhang J, Han Z, Chen H, Li Y Abstract Helicobacter pylori (H. pylori) is a gram-negative pathogen that colonizes gastric epithelial cells. The drug resistance rates of H. pylori have dramatically increased, causing persistent infections. Chronic infection by H. pylori is a critical cause of gastritis, peptic ulcers and even gastric cancer. In host cells, autophagy is stimulated to maintain cellular homeostasis following intracellular pathogen recognition by the innate immune defense system. However, H. pylori-induced autophagy is not consistent during acute and chronic infectio...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
AbstractThe Indian Society of Gastroenterology developed this evidence-based practice guideline for management of gastroesophageal reflux disease (GERD) in adults. A modified Delphi process was used to develop this consensus containing 58 statements, which were generated by electronic voting iteration as well as face-to-face meeting and review of the supporting literature primarily from India. These statements include 10 on epidemiology, 8 on clinical presentation, 10 on investigations, 23 on treatment (including medical, endoscopic, and surgical modalities), and 7 on complications of GERD. When the proportion of those who...
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Abstract Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the bacterial type IV secretion system. Delivered CagA then undergoes tyrosine phosphorylation at the Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs in its C-terminal region and acts as an oncogenic scaffold protein that physically interacts with multiple host signaling proteins in both tyrosine phosphorylation-dependent and -independent manners. Analysis of CagA using in vitro cultured gastric epithelial cells has indicated that ...
Source: Cellular and Molecular Immunology - Category: Molecular Biology Authors: Tags: Cell Mol Immunol Source Type: research
No abstract available
Source: European Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Letters to the Editor Source Type: research
AbstractAnkylosing spondylitis (AS) and undifferentiated spondylarthritis (uSpA) are related inflammatory diseases affecting the spine and joints with infections among possible etiological factors.Helicobacter pylori(H. pylori) may affect the development of inflammatory diseases. Thus, we hypothesized thatH. pylori infection affects AS and uSpA development. This cohort study was performed in Denmark with 56,000 patients from primary health care centers who were enrolled when a UBT was performed. They were followed for a median time of 8  years. From nationwide administrative registries, we extracted personal, diagnost...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Serine protease HtrA exhibits both proteolytic and chaperone activities, which are involved in cellular protein quality control. Moreover, HtrA is an important virulence factor in many pathogens including Helicob...
Source: Cell Communication and Signaling - Category: Molecular Biology Authors: Tags: Research Source Type: research
We have previously shown that Lactobacillus gasseri Kx110A1, a human stomach isolate, can colonize mouse stomach and reduce the initial colonization of Helicobacter pylori. Here, we investigated the role of sortase-dependent proteins (SDPs) involved in these functions by the construction of a mutant for srtA, the gene encoding the housekeeping sortase that covalently anchors SDPs to the cell surface. The srtA mutant showed a decrease in hydrophobicity and autoaggregation under acidic conditions, indicating the effect of SDPs on cell surface properties. Correspondingly, the srtA mutant lost the capacity to adhere to gastric...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusions: This study suggests a synergistic interaction betweenH. pyloriinfection, especiallycagA-positiveH. pylori,andPro/Pro genotype ofTP53 codon 72 polymorphism might play a significant role in the pathogenesis of GC in the Vietnamese population.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
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