Familial Aggregation and Heritability of Obstructive Sleep Apnea Using Children Probands

Conclusions:The differential results of heritability and familial aggregation of OSA in normal weight and overweight subgroups substantiated the recommendation of separating childhood OSA into normal weight and overweight subtypes. In the overweight subgroup, there may be obesity-independent components involved in the genetic variance of OAHI, although a significant proportion of the genetic variance is shared with obesity.Citation:Au CT, Zhang J, Cheung JYF, Chan KCC, Wing YK, Li AM. Familial aggregation and heritability of obstructive sleep apnea using children probands.J Clin Sleep Med. 2019;15(11):1561–1570.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research