Comparison of monoamine oxidase inhibition by cigarettes and modified risk tobacco products

In conclusion, we have demonstrated that specific pMRTPs, namely THS 2.2 and MESH 1.1, have a significantly lower MAO-inhibitory activity than 3R4F. These findings provide a basis for further investigation of the role of MAO inhibitors in cigarette addiction as well as the implications of the findings for abuse liability of pMRTPs in comparison with cigarettes.Graphical Abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research