EO3 - Early lesion detection with 18F-PSMA (DCFPyL) PET/CT in 248 patients with biochemically recurrent prostate cancer

Publication date: November 2019Source: European Urology Supplements, Volume 18, Issue 10Author(s): B.H.E. Jansen, M. Wondergem, F.M. Van Der Zant, T.M. Van Der Sluis, R.J.J. Knol, L.W.M. Van Kalmthout, O. Hoekstra, R.J.A. Van Moorselaar, D.E. Oprea-Lager, A.N. Vis
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research

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Condition:   Prostate Cancer Intervention:   Drug: rhPSMA-7.3 (18F) Injection Sponsors:   Blue Earth Diagnostics;   Parexel Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Prostate Cancer Intervention:   Drug: rhPSMA-7.3 (18F) Injection Sponsors:   Blue Earth Diagnostics;   Parexel Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   D011471;   D064129;   D035683;   D009360;   D014408 Intervention:   Diagnostic Test: Periodic ARV7 and miRNA evaluation Sponsor:   Azienda Ospedaliero-Universitaria Careggi Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 4 December 2019Source: Academic RadiologyAuthor(s): Moon Hyung Choi, Young Joon Lee, Seung Eun JungRationale and ObjectivesTo evaluate the change in clinical practice after implementation of prebiopsy biparametric MRI followed by targeted biopsy and the benefits of prebiopsy MRI based on real clinical practice.Materials and MethodsA total of 1,661 patients who underwent either transrectal biopsy or prebiopsy MRI for suspected prostate cancer between October 2015 and March 2018 were enrolled in this retrospective single-center study. To evaluate temporal changes in clinical practice, the s...
Source: Academic Radiology - Category: Radiology Source Type: research
Authors: Hu Z, Guo J, Zhao M, Jiang T, Yang X Abstract Predictive values of miR-129 and miR-139 for efficacy on patients with prostate cancer (PC) after chemotherapy and prognostic correlation were explored. Eighty-four patients with PC undergoing chemotherapy in The Third Affiliated Hospital of Qiqihar Medical University from January 2016 to January 2017 were enrolled as the observation group treated with DP regimen, and further 100 healthy individuals undergoing physical examination were enrolled as the control group. RT-qPCR was used to detect expression of serum miR-129 and miR-139. According to the clinical ef...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Publication date: Available online 26 November 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Anastasia Kanioura, Panagiota Petrou, Dimitris Kletsas, Angeliki Tserepi, Margarita Chatzichristidi, Evangelos Gogolides, Sotirios KakabakosAbstractThe enrichment of cancer cell population when in mixtures with normal ones is of great importance for cancer diagnosis. In this work, poly(methyl methacrylate) films have been processed applying different oxygen plasma conditions to fabricate surfaces with structure height ranging from 22 to more than 2000 nm. The surfaces were then evaluated with respect to adhesi...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
In this study, we used GaAu loaded mesoporous silica nanoparticles (Ga-Au@mSiO2) for the photothermal treatment of two prostate cancer cell lines. We systematically examined the nanocomposite form by various spectroscopic (UV–Vis, TGA and DTA) and electroscopic techniques (TEM and SEM including the elemental mapping analysis). After careful evaluation of the nanocomposite form, we performed cancer cell growth inhibition properties of the prostate cancer cell lines (DU145 and LNCaP). Also, we performed the photothermal effects of these nanocomposites on cell proliferation and apoptosis using different biochemical stai...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
We present a case of de novo adenosquamous carcinoma of the prostate treated with a multimodal approach including surgery, androgen-deprivation therapy, chemotherapy, and radiation.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
Bristol University researchers looked at how active 140,248 men were by looking at variations in their DNA - rather than relying on questionnaires.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Cholinergic α5 nicotinic receptor is involved in the proliferation and invasion of human prostate cancer cells. Oncol Rep. 2019 Nov 20;: Authors: Qi JC, Xue WY, Zhang YP, Qu CB, Lu BS, Yin YW, Liu KL, Wang DB, Li W, Zhao ZM Abstract Nicotinic acetylcholine receptor (nAChR) subunit α5 (α5‑nAChR) is involved in tumor cell proliferation, inhibition of apoptosis, progression of metastasis, and induction of angiogenesis in certain solid tumors. However, the role of α5‑nAChR in prostate cancer cell growth and metastasis is unclear. In the present study, the role of α5...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
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