EP013 - Potential receptors for targeted intraoperative imaging of lymph node metastases in bladder and penile cancer
Publication date: November 2019Source: European Urology Supplements, Volume 18, Issue 10Author(s): C. Van Der Fels, S. Palthe, M.C. Van Den Heuvel, I.J. De Jong
CONCLUSIONS: This report confirms that the high-dose regions in the bladder and rectum are more significant predictors of late toxicity and QOL after prostate SABR compared to low-dose regions. Caution must be taken to avoid high doses and hotspots in those organs. PMID: 31809979 [PubMed - as supplied by publisher]
ConclusionsIn the appropriately selected patient, OSS in upper tract, bladder and urethral carcinoma has comparable oncological outcomes to radical surgery and with the additional benefit of improved quality of life.
Stereotactic body radiation therapy (SBRT) is capable of delivering very large and precise dose of radiation, and has emerged as a primary treatment for low and intermediate risk prostate cancer [1,2]. Accurate imaging and tracking of the target regions allows clinicians to reduce treatment margins and maximally spare rectum, bladder, urethra and penile bulb . However, very sharp dose gradients and the proximity of critical structures to prostate requires precise verification of treatment plans [4,5].
PROSTATE cancer occurs in the prostate gland which is located just below the bladder. It wraps around the tub that carries semen and urine through the penis. Having this sexual ailment could be an advanced warning sign. Do you have it?
A tumour was found in the unnamed man's bladder after he visited the hospital in Queensland, unable to urinate. The cancer had spread to surrounding tissue which caused his penis to stay rigid.
Conclusions: Higher bone metastasis volume and higher total fluoride skeletal metastatic lesion uptake at the baseline F-18 NaF PET/CT demonstrated worse survival in urological malignancy patients with bone metastases treated. F-18 NaF PET/CT can be used for prediction of overall survival in urological malignancy patients with bone metastases.
Abstract While radiotherapy is widely used in cancer treatment, the benefits can be limited by radiation-induced damage to neighboring healthy tissues. We previously demonstrated that the anti-inflammatory compound dimethylaminoparthenolide (DMAPT) selectively induces radiosensitivity in prostate tumor tissue from transgenic adenocarcinoma of mouse prostate (TRAMP), while simultaneously protecting healthy tissues from 6 Gy whole-body radiation-induced apoptosis. Here, we examined the radioprotective effect of DMAPT on fibrosis in normal tissues after a partial-body fractionated radiation protocol that more closely...
EARLY detection of prostate cancer is not alway obvious however noticing a change in your urine, bladder and peeing habits could be a major warning and symptom of the cancer, because if present, the cancer has grown and put pressure on the tube that carries urine from the bladder out of the penis.
Conclusions: Insertion of HS in prostate cancer patients receiving combined HDR and EBRT is safe and has resulted in a significant radiation dose reduction to the rectum, resulting in significantly less acute GI toxicity and a trend towards less late GI toxicity. PMID: 30911304 [PubMed]
Conclusion: This study can be taken as a small step toward making the registry of patients with urogenital tumors providing valuable information regarding the frequency, clinical presentation, and histological spectrum. Large population-based studies for a longer duration of time across both males and females are needed in the ever-changing trends of urogenital tumors.