The Relationship Between Cadaveric Allograft Skin and HLA-Sensitivity in Burn Patients

Condition:   Burns Intervention:   Biological: Skin allograft Sponsors:   Virginia Commonwealth University;   AlloSource Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Conclusions &discussion: This paper is designed as a guideline and instruction manual to help those with less experience through particular situations in surgical burn care. Early excision and immediate coverage of the burn wounds represent nowadays the standard care for extensive burned patients. For patients with massive thermal injury, temporary coverage with allografts is essential. The use of allograft has multiple benefits because it plays both as physiologic and mechanical barriers. PMID: 31803300 [PubMed]
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
ConclusionThe current study demonstrated that the properties of the ablative well (depth and width) are not linearly correlated with laser pulse energy, with only a small increase in well depth at energies between 70 and 150 mJ. Overall, the study suggests that there is little difference in outcomes as a function of laser energy. Fractional CO2 laser therapy did not result in any statistically significant benefit to scar properties assessed by quantitative, objective measures, thus highlighting the need for additional clinical investigation of laser therapy efficacy with non-treated controls and objective measures of outcome.
Source: Burns - Category: Dermatology Source Type: research
The objective of this study was to characterize healthcare resource utilization, treatment patterns, and cost of care for thermal burn patients in two large privately insured populations in the United States who underwent inpatient autografting between 01/01/2011 and 06/30/2016. Patient demographics, clinical characteristics, healthcare resource utilization, and total cost were examined during baseline (one year before the initial hospitalization with autografting) and two-year evaluation period. There was a substantial economic burden on thermal burn patients who received inpatient autografts (HIRD® database [HIRD]: N...
Source: Burns - Category: Dermatology Source Type: research
Condition:   Burns Intervention:   Biological: Skin allograft Sponsors:   Virginia Commonwealth University;   AlloSource Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 13 November 2019Source: Arthroscopy TechniquesAuthor(s): Burak Altintas, Frank Martetschläger, Erik M. Fritz, Ryan J. Warth, Joshua A. Greenspoon, Travis C. Burns, Nicole L. Anderson, Peter J. MillettAbstractSurgical exposure of the glenoid after previous coracoid process transfer is technically challenging as a result of distorted anatomy, obliterated soft-tissue planes, and adhesive scar tissue, which poses additional risk to adjacent neurovascular structures. The purpose of this article is to present a technique for glenoid exposure following coracoid transfer that involves tenoto...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
The objective of this study is to report on the outcomes of dehydrated amniotic membrane as a biologic skin dressing in pediatric facial burn injury compared to cadaveric allografts. Methods: Retrospective review of data collected from our institutional burn registry from 2012 to 2016. The study population included patients younger than 16 years with facial burns. Patients between 2012 and 2014 received cadaveric allografts, whereas during 2015 to 2016 patients received dehydrated human amniotic/chorionic membrane as standard treatment. Demographic characteristics and outcome measures were compared between the 2 groups....
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Clinical Studies Source Type: research
Publication date: Available online 20 October 2019Source: BurnsAuthor(s): Luiz Philipe Molina Vana, Cláudia Naves Battlehner, Marcelo Alves Ferreira, Elia Garcia Caldini, Rolf Gemperli, Nivaldo AlonsoAbstractThe advent of dermal regeneration templates has fostered major advances in the treatment of acute burns and their sequelae, in the last three decades. Both data on morphological aspects of the newly-formed tissue, and clinical trials comparing different templates, are few. The goal of this study was to prospectively analyze the outcome of randomized patients treated with two of the existing templates, followed b...
Source: Burns - Category: Dermatology Source Type: research
Condition:   Burns Interventions:   Other: Early Mobilization;   Other: Late Mobilization Sponsor:   Sunnybrook Health Sciences Centre Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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